It has been demonstrated that, in the bone extracellular matrix (ECM), integrins and growth factor receptors (GFRs) engage in synergistic signaling to guide bone healing and regeneration. This review provides a comprehensive overview of current strategies using ECM‐derived peptides to recreate the cellular microenvironment and harness synergistic ...
Lluís Oliver‐Cervelló +2 more
wiley +1 more source
Ultrapliable bioelectronic interface for mechanosensitive cardiac electrophysiology. [PDF]
Yu J +18 more
europepmc +1 more source
Microproteins are hidden treasures encoded by the “dark proteome” but remain largely underexplored due to the lack of highly efficient tools. We developed a molecularly imprinted polymers (MIPs)‐based toolbox (CLAIMID) to achieve accelerated and ultrasensitive microproteins validation at multiple biological scales (single living cells, cell populations,
Hui He +10 more
wiley +1 more source
Protein Corona as a Result of Interaction of Protein Molecules with Inorganic Nanoparticles. [PDF]
Sarimov RM +4 more
europepmc +1 more source
Charge-Transport Mechanisms in CuInSe x S 2� x Quantum-Dot Films [PDF]
Fuhr, Addis S +7 more
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De Novo Multi‐Mechanism Antimicrobial Peptide Design via Multimodal Deep Learning
Current AI‐driven peptide discovery often overlooks complex structural data. This study presents M3‐CAD, a generative pipeline that leverages 3D voxel coloring and a massive database of over 12 000 peptides to capture nuanced physicochemical contexts.
Xiaojuan Li +23 more
wiley +1 more source
Intravital microscopy for nanomedicine: investigating nanoparticle-tissue interactions in the native state. [PDF]
Saladino GM.
europepmc +1 more source
This work introduces an open‐source all‐optical platform for functional phenotyping of human stem cell‐derived neurons. The system integrates optogenetics, calcium imaging, automated acquisition, and analysis to resolve single‐cell and network activity, enabling longitudinal measurements, disease modeling, and pharmacological screening in preclinical ...
Wardiya Afshar‐Saber +12 more
wiley +1 more source
Laser-Ablated Gold Nanoparticles as Tunable Contrast Agents for Preclinical Imaging. [PDF]
Finogenova Y +9 more
europepmc +1 more source
The Relationship between Indigenous Rights, Citizenship and Land in Territorial Alaska: How the Past Opened the Door to the Future [PDF]
Swensen, Thomas M.
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