Results 151 to 160 of about 245,386 (305)

A Plug‐and‐Play Platform for Customizing Multivalent Degraders and Degrader‐Drug Conjugates

Advanced Science, EarlyView.
Membrane proteins remain challenging targets for conventional TPD approaches. Here, the authors develop UPTAB, a modular platform leveraging ultrahigh‐affinity orthogonal Im/CL protein pairs for lysosomal degradation of membrane proteins. Mono‐targeted (Type‐I), dual‐targeted (Type‐II), and tri‐targeted (Type‐III) UPTABs enable simultaneous degradation
Mengqing Zhao, Yan Deng, Jianjian Han, Yong Xie, Kai Bao, Lixin Ma, Lilong Liu, Wuxiang Mao   +7 more
wiley   +1 more source

How experience with tone in the native language affects the L2 acquisition of pitch accents. [PDF]

Front Psychol, 2022
Zahner-Ritter K, Zhao T, Einfeldt M, Braun B.   +3 more
europepmc   +1 more source

PlantGFM: A Genomic Foundation Model for Discovery and Creation of Plant Genes

Advanced Science, EarlyView.
A plant genomic foundation model pre‐trained on 12 species enables both accurate gene prediction and de novo gene design. Through AI‐human knowledge screening, seven designed sequences showed transcriptional activity in plants, with two expressing stable proteins—demonstrating the first DNA‐RNA‐protein expression of LLM‐generated genes in plants and ...
Changhao Li, Qizhe Zhang, Hanchen Chen, Kepeng Lin, Chengfang Luo, Mengying Yang, Wei Xu, Fan Yao, Jianbing Yan, Qing‐Yong Yang, Xuehai Hu   +10 more
wiley   +1 more source

Tatar ethnopedagogy and native language

Историческая этнология, 2016
Every nation in the process of historical development creates a certain system of national education. The study of the history and theory of national education is called ethnopedagogy.
Grif T. Khayrullin
doaj  

Patients' knowledge about medicines improves when provided with written compared to verbal information in their native language. [PDF]

PLoS One, 2022
T R, I U H, M Y M, P G.
europepmc   +1 more source

A:shiw A:wan Ts’inakya Haydoshnanne

This is a language resource that incorporates the Zuni alphabet and the correct grammar punctuation in ...
Zuni Language Development Program
core  

ProSiteHunter: A Unified Framework for Sequence‐Based Prediction of Protein‐Nucleic Acid and Protein‐Protein Binding Sites

Advanced Science, EarlyView.
This study proposed a unified sequence‐based framework for protein binding site prediction, which adopted a tri‐track semantic multi‐source feature fusion strategy to effectively capture diverse macromolecular interaction sites and further improved the accuracy of antibody‐antigen interaction prediction.
Dongliang Hou, Qihang Zhen, Zexin Lv, Xinyue Cui, Suhui Wang, Minghua Hou, Zhan Zhou, Xiaogen Zhou, Guijun Zhang   +8 more
wiley   +1 more source

Physical Education with Eduball Stimulates Non-Native Language Learning in Primary School Students. [PDF]

Int J Environ Res Public Health, 2022
Cichy I, Kruszwicka A, Palus P, Przybyla T, Schliermann R, Wawrzyniak S, Klichowski M, Rokita A.   +7 more
europepmc   +1 more source

AI‐Physics‐Experiment Trinity for Integrated Protein Dynamics Modeling

Advanced Science, EarlyView.
This review unites experiments, physics‐based simulations, and AI as a synergistic triad for protein dynamics modeling. It highlights integrative strategies, resolves sampling and forcefield bottlenecks, and outlines challenges and future directions for accurate, interpretable conformational ensemble prediction.
Chen Shi, Minying Low, Peng Xiu, Kresten Lindorff‐Larsen, Yong Wang   +4 more
wiley   +1 more source

The Perception and Production of SSBE vowels by Syrian Arabic learners:The Foreign Language Model [PDF]

, 2008
This thesis presents an examination of the perception and production of Standard Southern British English (SSBE) vowels by Syrian Arabic (SA) Foreign language (FL) learners.
Alhussein Almbark, Rana
core