Results 51 to 60 of about 166,849 (263)
ADP‐ribosylation: An emerging regulator of the epigenome
Molecular Oncology, EarlyView.ADP‐ribosylation has emerged as a dynamic epigenetic signaling mechanism that modifies histones and chromatin‐associated proteins. Through coordinated PARylation and MARylation, it integrates with other histone modifications to regulate chromatin structure, transcription factor activity, and gene expression, influencing genome function and disease ...
Cristel V. Camacho +2 more
wiley +1 more source
FEBS Open Bio, EarlyView.Abruptly changing from aerobic to anaerobic conditions (sudden anaerobization) induced growth inhibition and a significant increase in intracellular labile ferrous iron in the aerotolerant anaerobe Amphibacillus xylanus. We found that free flavins mediate efficient electron transfer from NADH to ferric iron under anaerobic conditions, suggesting that ...
Shinya Kimata +13 more
wiley +1 more source
Sentences and Documents in Native Language Identification [PDF]
, 2018 Starting from a wide set of linguistic features, we present the first in depth feature analysis in two different Native Language Identification (NLI) scenarios. We compare the results obtained in a traditional NLI document classification task and in a newly introduced sentence classification task, investigating the different role played by the ...
Cimino A +3 more
openaire +4 more sources
Directed evolution of enzymes at the crossroads of tradition and innovation
FEBS Open Bio, EarlyView.An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova +2 more
wiley +1 more source
Delicate Patterns of Colligations: A Corpus-based Study of Prepositions
Corporum, 2023 The term colligation evidently highlights syntagmatic patterns of language. Basically, it investigates grammatical attractions between different lexical items based on their grammatical category (Firth, 1968).
Attia Rasool +2 more
doaj
ЭТАПЫ РАЗВИТИЯ НАЦИОНАЛЬНОЙ ШКОЛЫ В КАЛМЫКИИ (1993 - 2003 гг.)
Oriental Studies, 2018 The paper is devoted to the development of national school in Kalmykia as one of mechanisms which allows the people to keep culture, transferring from generation to generation the experience, saved by centuries, supporting communication of times ...
Evgeniya Viktorovna Sartikova
doaj +1 more source
FEBS Open Bio, EarlyView.Miniaturized flow chip platform enabling continuous perfusion and longitudinal multiphoton 3D imaging of vascular smooth muscle cell constructs under physiological flow. Brightfield imaging guides region selection, while CellTracker Green and mRuby‐labeled fetuin‐A visualize cells and mineral deposition, respectively. Magnesium supplementation markedly
Vytautas Kučikas +6 more
wiley +1 more source
Evolution‐guided yeast complementation reveals functional differences in human PSPH variants
FEBS Open Bio, EarlyView.Ancient genomes can help guide which human genetic variants are tested experimentally. This study applies that idea to PSPH, a gene involved in serine biosynthesis, and uses high‐throughput yeast complementation to compare variant function. The findings reveal measurable differences among selected alleles and illustrate the value of evolution‐guided ...
Mauricio Campa‐Álvarez +6 more
wiley +1 more source
The achievements and development prospects of teaching Polish as a non-native language
Acta Universitatis Lodziensis: Kształcenie Polonistyczne Cudzoziemców, 2020 The discussion begins by indicating the strengths and weaknesses of teaching Polish as a non-native language today while focussing on how approaches to individual issues have changed.
Władysław T. Miodunka
doaj +1 more source
Dual native G‐quadruplex folding is associated with chromatin looping at the MYC locus
FEBS Open Bio, EarlyView.BG4‐detectable G‐quadruplex (G4) in HaCaT and NHEK keratinocytes identified folded and unfolded G4s enriched at promoters/TSSs and active enhancers, whereas unfolded G4s also overlapped weak/poised enhancers. At MYC–PVT1, 3C‐qPCR detected enhancer–promoter looping only when G4s were simultaneously folded at both regulatory elements under native ...
Dieila Giomo de Lima +7 more
wiley +1 more source