Results 71 to 80 of about 14,893 (259)

Bibliotecas indígenas en Australia y Nueva Zelanda: una revisión bibliográfica

Revista Interamericana de Bibliotecología, 2007
Presenta una revisión bibliográfica y un estado actual de la cuestión sobre bibliotecas para pueblosoriginarios en un contexto internacional. La recolección de recursos informativos se enfoca en los dospaíses de Oceanía: Australia y Nueva Zelanda, en los
Edgardo Civallero
doaj  

PRMT1‐Mediated LDHA Methylation Drives STAT3 Lactylation to Orchestrate Intestinal Inflammation and Tumorigenesis

Advanced Science, EarlyView.
This study identifies an immunometabolic axis wherein SAM‐driven PRMT1 methylates LDHA, enhancing its activity. The resultant lactate induces STAT3 K709 lactylation, which stabilizes an active conformation to promote STAT3 phosphorylation and IL‐10 expression.
Hui Wang, Mengyu Zhang, Weipeng Gong, Jiaxuan Wu, Junping Zhang, Wenxiu Zhang, Yue Liu, Kui Wang, Canhua Huang, Jun Zhou, Sijin Wu, Yan Li, Tianliang Li   +12 more
wiley   +1 more source

Earth Science Data Repositories: Implementing the CARE Principles

Data Science Journal
Datasets carry cultural and political context at all parts of the data life cycle. Historically, Earth science data repositories have taken their guidance and policies as a combination of mandates from their funding agencies and the needs of their user ...
Margaret O’Brien, Ruth Duerr, Riley Taitingfong, Andrew Martinez, Lourdes Vera, Lydia L. Jennings, Robert R. Downs, Erin Antognoli, Talya ten Brink, Nicole B. Halmai, Dominique David-Chavez, Stephanie Russo Carroll, Maui Hudson, Pier Luigi Buttigieg   +13 more
doaj   +1 more source

Conservation Refugees: The Hundred-Year Conflict between Global Conservation and Native Peoples

Refuge, 2014
Conservation Refugees: The Hundred-Year Conflict between Global Conservation and Native Peoples Mark Dowie MIT ISBN: 9780262012614, pp.
Francis Massé
doaj   +1 more source

Phosphorylation‐Facilitated CKB Lactylation At K11 By GCN5 Enhances Creatine Kinase Activity and Mitigates Neuronal Damage After Cerebral Ischemia‐Reperfusion

Advanced Science, EarlyView.
This study uncovers hierarchical coordination between K11 lactylation and S199 phosphorylation of CKB in cerebral ischemia‐reperfusion injury. Such dual modifications potentiate CKB enzymatic function, remodel energy metabolism, alleviate oxidative stress and neuronal damage, and represent a viable therapeutic target for stroke treatment.
Chao Duan, Ruolin Zhang, Shihui Ding, Ying Feng, Tao Shen, Ziwei Wang, Wendai Bao, Ke Shui, Jun Qin, Jun Chen, Min Zhang, Zijing Ren, Dongmei Zhao, Xingrong Guo, Zhibing Ai, Xin Yang, Peiyang Zhou, Zhiqiang Dong   +17 more
wiley   +1 more source

Combating Inflammation and Promoting Anabolism in Osteoarthritic Cartilage Defect With an MMP13‐Sensing Dual‐Drug Scaffold

Advanced Science, EarlyView.
ABSTRACT Osteoarthritis (OA) is a widespread degenerative joint condition marked by progressive cartilage breakdown, and a chronic inflammatory microenvironment, where conventional therapies largely fail to halt disease progression. To address this unmet need, an intra‐articularly implantable, disease‐responsive scaffold was developed for combinatorial
Zhen Zhang, Bangheng Liu, Yulei Mu, Huiqun Zhou, Liang Ma, Chenjie Xu, Dong‐An Wang   +6 more
wiley   +1 more source

Mitigating Cancer Therapy–Related Cognitive Impairment by Targeted Activation of Undruggable Phosphatase

Advanced Science, EarlyView.
An RVG‑engineered exosomal saRNA delivery system (RVG‑EVs‑saPtpro) effectively targets and activates hippocampal PTPRO, functioning as a “molecular brake” to alleviate cancer therapy‑related cognitive impairment (CTRCI) by enhancing neuronal survival, neurogenesis, and synaptic plasticity.
Zhimeng Yao, Yuhua Meng, Huanyi Li, Yinhui Jiang, Xiaona Lin, Mengyuan Hu, Qing Liu, Xiaofu Qiu, Hongzheng Ren, Yunlong Pan, Bin Pan, Zexiong Guo, Shuyao Zhang, Dianzheng Zhang, Li Yang, Shegan Gao, Weijing Deng, Jianfan Chen, Hao Zhang   +18 more
wiley   +1 more source

A Pollen‐Enhanced Bionic Mechanoreceptor Induced by Asymmetric Ionic Convection in Hydrogel for Sensory‐Augmented Prostheses

Advanced Science, EarlyView.
This work proposed a pollen‐enhanced bionic mechanoreceptor based on ionic convection. Leveraging the ion anchoring effect of the pollen particle, the output performance could be ∼12 times higher than the original state. By employing deep learning models as AI brains, the feasibility of a sensory‐augmented prosthesis consisting of a pollen‐enhanced ...
Zi Hao Guo, Jingyu Deng, Yanzhang Xu, Chenchen Zhou, Yangshi Shao, Xiong Pu, Munho Kim, Namjoon Cho   +7 more
wiley   +1 more source

«COLLECTIVE RIGHTS» OF ETHNIC COMMUNITIES: EXAMINATION OF SOCIAL AND LEGAL CONCEPTS

Модернизация, инновация, развитие, 2016
Attitude to so-called «collective rights» of ethnic groups as to a basis of ethno-national politics of every progressive state and of the whole global social community has lately become popular.
M. A. Yuzhanin
doaj  

Botulism in Native Peoples - An Economic Study

Journal of Food Protection, 1988
Type E botulism occurs regularly in scattered locations in the Canadian Arctic and northern coastal British Columbia from the consumption of improperly fermented fish and marine mammal products by native peoples, with an average of eight cases and 1.5 deaths each year.
openaire   +2 more sources