Results 41 to 50 of about 457,830 (257)
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
BMC Plant BiologyBackground Cinnamomum camphora is a valuable aromatic oil-producing species with significant economic and industrial importance. Linalool, a monoterpenoid compound and a major component of camphor leaf essential oil, is widely used in cosmetics, food ...
Hao Rong +7 more
doaj +1 more source
Trees, Forests and PeopleConverting monoculture plantations into mixed stands is a key strategy for enhancing soil carbon sequestration. The mechanisms behind soil organic carbon (SOC) turnover and its temperature response at different mixed densities are unclear.
Xiulan Zhang +8 more
doaj +1 more source
Liver organoids: modelling complexity in homeostasis and disease
FEBS Letters, EarlyView.Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley +1 more source
A CcMYB90-CcCHS1 module regulates flavonoid biosynthesis during pericarp darkening in
Industrial Crops and ProductsIn the camphor tree ( Cinnamomum camphora L.), bioactive metabolites are found in different parts, including the leaves, fruits, and stems; its fruit, particularly the pericarp, is abundant in flavonoids and volatile compounds.
Zheng Qin +6 more
doaj +1 more source
Ilex decapetala (Aquifoliaceae), a new holly species from Vietnam revealed by molecular and morphological approaches [PDF]
PhytoKeysA new species, Ilex decapetala, is described and illustrated from central Vietnam. It is distinguished by its female flowers with (8–)9–10(–11) pink petals (mostly 10); such a high floral merism is rare within the genus and, on top of this rarity, no ...
Yi Yang +8 more
doaj +3 more sources
Antibiotics, 2023 The increase in antimicrobial resistance and tolerance over the years has become a serious public health problem, leading to the inevitable development of alternative antimicrobial agents as substitutes for industrial pharmaceutical antibiotics targeting
Caglar Ersanli +7 more
doaj +1 more source
FEBS Letters, EarlyView.Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell +2 more
wiley +1 more source
Foods, 2023 In the last decades, Primula veris subsp. veris (roots and flowers) has been over harvested through legal and illegal ways in Greece, due to its extremely high commercial demand, as it is used in industry because of its well-known therapeutic properties.
Konstantia Graikou +5 more
doaj +1 more source
Structural and biochemical analysis of a B12 superbinder
FEBS Letters, EarlyView.BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices +3 more
wiley +1 more source