Results 61 to 70 of about 449,411 (257)

Structural studies and functional engineering of NanX: an anhydro‐sialic acid transporter from Escherichia coli

FEBS Open Bio, EarlyView.
Biophysical characterisation shows that NanX, a membrane transport protein from the major facilitator superfamily (MFS), forms both monomers and dimers after purification. AlphaFold modelling and substrate docking provide information on residues likely involved in substrate recognition for NanX and another MFS member, NanT.
Michael C. Newton‐Vesty, Kelsi R. Hall, Zachary D. Tillett, Liam S. Turk, James S. Davies, Michael J. Currie, Hamish G. Brown, Sepideh Valimehr, Peter D. Mace, Andrew E. Whitten, Santosh Panjikar, Eric Hanssen, Rachel A. North, Renwick C.J. Dobson   +13 more
wiley   +1 more source

Synthesis and crystal structure of methyl 4-(2-ethoxy-2-oxoethoxy)-3,5-dimethoxybenzoate, C14H18O7

Zeitschrift für Kristallographie - New Crystal Structures
C14H18O7, orthorhombic, P212121 (no. 19), a = 4.3538(6) Å, b = 12.7630(19) Å, c = 26.493(4) Å, V = 1,472.2(4) Å3, Z = 4, R gt(F) = 0.0414, wR ref (F 2) = 0.1043, T = 296(2) K.
Shang Xiao-ming, Luo Ying, Chen Nuo, Wang Zong-de, Luo Hai   +4 more
doaj   +1 more source

Quantitative Lipidomics Reveals Dynamic Lipid Profiles in Cinnamomum camphora Seed Kernels at Different Developmental Stages

Plants
Cinnamomum camphora seed kernels are a potentially valuable fatty oil resource; however, their lipid composition and dynamic changes during development remain poorly understood.
Han Xie, Yongjie Zheng, Yueting Zhang, Chenglin Luo, Ting Zhang, Wanwen Yu, Xuhui Zhang, Xinliang Liu   +7 more
doaj   +1 more source

Adenosine triphosphate as a modulator of protein interactions and stability

FEBS Open Bio, EarlyView.
ATP is best known as the cell's energy currency, but it also shapes how proteins fold, interact, aggregate and form biomolecular condensates. This review explains the emerging physical principles behind these effects, including weak binding to charged protein regions, magnesium‐dependent behaviour and concentration‐dependent control of protein ...
Shuyuan Tan, Robin Curtis
wiley   +1 more source

Design, synthesis, and biological evaluation of pyridylamide-type neonicotinoid derivatives based on flupyrimin scaffold

BMC Chemistry
The sucking pests such as aphids, planthoppers, and whiteflies pose a significant threat to global crop productivity, causing estimated losses of up to 40% in affected areas. Reports indicate that resistance to traditional agents such as imidacloprid has
Qingwen Fang, Ying Wen, Jie Wang, Xuliang Nie, Yueming Xu, Guozheng Huang, W. W. W. W. Kandegama, Shangxing Chen, Yong Ye, Dayong Peng   +9 more
doaj   +1 more source

Development and Validation of Species-Specific KASP and SCAR Markers for the Rapid Identification of the Endangered Orchid Calanthe aristulifera

Plants
Calanthe aristulifera is a critically endangered orchid species of profound horticultural and ecological significance. However, establishing its species integrity is complicated by frequent natural introgression with sympatric relatives, such as C ...
Jung Eun Hwang, Seongjun Kim, Hyeong Bin Park, Sung Min Han, Yubin Lee, Chang Woo Lee, Young-Joong Kim   +6 more
doaj   +1 more source

Structural and biochemical insights into the thermostable esterase Ta0887 from Thermoplasma acidophilum

FEBS Open Bio, EarlyView.
In this study, a novel esterase from the thermoacidophilic archaeon Thermoplasma acidophilum was biochemically and structurally characterized. Our results demonstrate that Ta0887 is a highly thermostable esterase that preferentially hydrolyzes p‐nitrophenyl hexanoate and possesses an α‐helical cap domain that likely contributes to its substrate ...
Alejandro Delgado‐Rey, Miriam Livier Llamas‐García, Gabriela M. Montero‐Morán, Leticia Santos, Samuel Lara‐González   +4 more
wiley   +1 more source

Design, Synthesis and Crystal Structure of a Novel Fluorescence Probe for Zn²⁺ Based on Pyrano[3,2-c] Carbazole

Molecules
Zinc is a trace element, which plays an important role in many biological processes. The deficiency of zinc will lead to many diseases. Thus, it is of great significance to develop fast and efficient quantitative detection technology for zinc ions.
Ziyin Xie, Qingwen Fang, Shuzhen Xiao, Jie Wang, Ping Lin, Chunmei Guo, Huihua Cao, Zhongping Yin, Lihong Dong, Dayong Peng   +9 more
doaj   +1 more source

A minimal cellulosome‐like system in Cellulosilyticum lentocellum

FEBS Open Bio, EarlyView.
Cellulose‐degrading bacteria typically use cellulosomes, large multi‐enzyme complexes on a scaffold protein. In Cellulosilyticum lentocellum, we characterise a far smaller arrangement, a single scaffold bound to one cellulase through a single cohesin‐dockerin interaction.
John Allan, Amias Alstrom‐Moore, Gary W Black   +2 more
wiley   +1 more source

Genetic dissection of human ABCE1 in yeast reveals separable requirements for ribosome recycling and suppression of aberrant reinitiation

FEBS Open Bio, EarlyView.
Human ABCE1 cannot functionally replace its yeast ortholog. Yeast–human chimera analysis identified NBD1 as a major interspecies barrier. Genetic screening yielded hABCE1 revertants that rescue yeast viability but fail to suppress aberrant translation reinitiation in the 3′ UTR.
Eriko Nakata, Yuxin Li, Kei Endo, Koichi Ito   +3 more
wiley   +1 more source