Results 61 to 70 of about 5,312,271 (270)

Liver organoids: modelling complexity in homeostasis and disease

FEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

Comparison of a native and a non-native insular reptile species [PDF]

Journal of Tropical Ecology, 2015
Abstract:This study compared the life histories ofHemidactylus frenatus, a significant invasive gecko, andPhyllodactylus palmeus, a Honduran endemic, over 10 wk, June–August 2013 at 12 study sites on the Honduran island of Cayo Menor of the Cayo Cochinos archipelago whereH. frenatusarrived in 2008.
Nicholson, DJ, Hassall, C, Frazier, JA
openaire   +2 more sources

Functional comparison of EncB and EncC cargo proteins in iron storage within the Myxococcus xanthus encapsulin

FEBS Letters, EarlyView.
Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell, Thomas Walther, Egbert Hoiczyk   +2 more
wiley   +1 more source

Increased stability of a subtropic bamboo forest soil bacterial communities through integration of water and fertilizer management compared to conventional management

BMC Plant Biology
Background Conventional management (CM), substantial fertilization and flooding irrigation, has led to soil acidification, the decrease in soil bacterial diversity in bamboo forests.
Yi Li, Zacchaeus G. Compson, Xiaobao Kuang, Lin Yu, Qingni Song, Jun Liu, Dongmei Huang, Hanchang Zhou, Siyuan Huang, Ting Li, Qingpei Yang   +10 more
doaj   +1 more source

Native frog (Leiopelma spp.) recovery plan, 2013–2018 [PDF]

, 2014
This report outlines a plan to secure the survival of New Zealand\u27s native frogs. Abstract Native frogs were formerly widespread and common throughout New Zealand.

core  

Structural and biochemical analysis of a B12 superbinder

FEBS Letters, EarlyView.
BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices, Jacob J. Whittaker, Dirk J. Slotboom, Albert Guskov   +3 more
wiley   +1 more source

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

FEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge, Vivian Pogenberg, Alexander Baumgart, Bente Siebels, Hartmut Schlüter, Michael Hecht‐Bucher, Aymelt Itzen   +6 more
wiley   +1 more source

Vertically distinct patterns of soil carbon and nitrogen stock depletion associated with Moso bamboo encroachment into subtropical forests

Frontiers in Plant Science
Moso bamboo (Phyllostachys edulis) expansion is strongly associated with soil degradation in subtropical forests, but the underlying abiotic and biotic factors regulating soil organic carbon (SOC) and total nitrogen (TN) stocks across different stands ...
Jianhong Xu, Jianhong Xu, Lei Hua, Wenjie Long, Juan Liu, Dongnan Hu, Songze Wan, Songze Wan   +7 more
doaj   +1 more source

Invisible but not inaccessible—Revealing transient oligomers formed by intrinsically disordered proteins with solution NMR and complementary methods

FEBS Letters, EarlyView.
Transient oligomers formed by intrinsically disordered proteins may be ‘invisible’ to direct detection yet remain accessible to solution NMR through equilibrium‐exchange measurements and pressure‐jump experiments. Complementary methods report on mass, stoichiometry, selected distance distributions, morphology, and internal packing.
Martin D. Gelenter, Ad Bax
wiley   +1 more source

Membrane composition and thermodynamic identity as boundaries of life for synthetic cell research

FEBS Letters, EarlyView.
What makes a cell a cell? The boundary of a living cell is not just a wall. Read as a Markov blanket, the membrane separates internal from external states, generating identity and non‐equilibrium order. Can this identity be rebuilt from scratch in a synthetic cell?
Caterina Presutti, Bert Poolman
wiley   +1 more source