Results 51 to 60 of about 5,312,271 (270)
Reconstructing enzyme evolution by protein engineering
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Background Cinnamomum camphora is a valuable aromatic oil-producing species with significant economic and industrial importance. Linalool, a monoterpenoid compound and a major component of camphor leaf essential oil, is widely used in cosmetics, food ...
Hao Rong +7 more
doaj +1 more source
Converting monoculture plantations into mixed stands is a key strategy for enhancing soil carbon sequestration. The mechanisms behind soil organic carbon (SOC) turnover and its temperature response at different mixed densities are unclear.
Xiulan Zhang +8 more
doaj +1 more source
An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg +14 more
wiley +1 more source
In the camphor tree (Cinnamomum camphora L.), bioactive metabolites are found in different parts, including the leaves, fruits, and stems; its fruit, particularly the pericarp, is abundant in flavonoids and volatile compounds.
Zheng Qin +6 more
doaj +1 more source
Ilex decapetala (Aquifoliaceae), a new holly species from Vietnam revealed by molecular and morphological approaches [PDF]
A new species, Ilex decapetala, is described and illustrated from central Vietnam. It is distinguished by its female flowers with (8–)9–10(–11) pink petals (mostly 10); such a high floral merism is rare within the genus and, on top of this rarity, no ...
Yi Yang +8 more
doaj +3 more sources
In the last decades, Primula veris subsp. veris (roots and flowers) has been over harvested through legal and illegal ways in Greece, due to its extremely high commercial demand, as it is used in industry because of its well-known therapeutic properties.
Konstantia Graikou +5 more
doaj +1 more source
Seed rain and soil seed banks limit native regeneration within urban forest restoration plantings in Hamilton City, New Zealand [PDF]
Restoration of native forest vegetation in urban environments may be limited due to isolation from native seed sources and to the prevalence of exotic plant species.
Overdyck, Elizabeth, Clarkson, Bruce D.
core
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
The increase in antimicrobial resistance and tolerance over the years has become a serious public health problem, leading to the inevitable development of alternative antimicrobial agents as substitutes for industrial pharmaceutical antibiotics targeting
Caglar Ersanli +7 more
doaj +1 more source

