Results 191 to 200 of about 457,830 (257)

Compensatory Mitophagy via NEDD4/HIF‐1α/BNIP3 Pathway Restrains EndMT and Renal Allograft Interstitial Fibrosis Induced by TNFα

Advanced Science, EarlyView.
The role of TNFα in the process of renal allograft interstitial fibrosis is complex and multifaceted. As it can promote renal allograft interstitial fibrosis by inducing mitochondrial dysfunction and EndMT, and also mediating compensatory mitophagy through the NEDD4–HIF‐1α–BNIP3 pathway, which clears damaged mitochondria and inhibits EndMT, thereby ...
Dengyuan Feng, Qinghuan Shen, Junqi Zhang, Jiawen Liu, Zeping Gui, Zijie Wang, Qianguang Han, Shuang Fei, Hao Chen, Li Sun, Jun Tao, Zhijian Han, Xiaobing Ju, Min Gu, Jianjian Zhang, Ruoyun Tan   +15 more
wiley   +1 more source

Synthesis and crystal structure of 4-(difluoromethyl)-1-methyl-N-(pyridin-3-yl)-1H-pyrazole-3-carboxamide hydrate, C11H12F2N4O2

Zeitschrift für Kristallographie - New Crystal Structures
Huang Hao-Wen, Liu Hao-Hong, Lin Si-Tong, Gan Xian-Nv, Zhang Ji   +4 more
doaj   +1 more source

Reseeding Native Species Promotes Community Stability by Improving Species Diversity, Niche, and Interspecific Relationships in the Desert Steppe of Northwest China. [PDF]

Ecol Evol
Jiang H, Zhou Y, Li W, Lu Q, Xu D, Ma H, Ma X, Tian X.   +7 more
europepmc   +1 more source

Transcription Factor Promiscuity Drives Regulatory Rewiring and Evolvability in Gene Networks in Bacteria

Advanced Science, EarlyView.
When a master transcription factor (TF) is lost, bacteria can rapidly rewire gene regulatory networks by co‐opting related regulators. Using experimental evolution in Pseudomonas fluorescens, we show that TF promiscuity (low‐level, non‐cognate binding) provides the raw material for rewiring. Successful co‐option follows a predictable hierarchy governed
Tiffany B. Taylor, Alan M. Rice
wiley   +1 more source

Eco-evolutionary experience and behavioral innovation in interactions with non-native species. [PDF]

iScience
Ruland F, Meltl AA, Neugebauer MS, Jeschke JM.   +3 more
europepmc   +1 more source

Underground Signals: The Ecological Power of Root Volatiles

Advanced Science, EarlyView.
Root volatiles mediate rhizosphere chemical communication, shaping interactions among plants, microbes, herbivores, and natural enemies. Their production, transport, and perception underpin ecological adaptation, multitrophic interactions, and plant resilience, offering opportunities for sustainable crop protection, resilient agroecosystems, and ...
Xueyao Cao, Nanli Song, François Verheggen, Meritxell Pérez‐Hedo, Andrea Clavijo McCormick, Antonino Cusumano, Arthur de Fouchier, Bing Wang, Chen‐Zhu Wang, Emmanuelle Jacquin‐Joly, Gary W. Felton, Geoff M. Gurr, Hao Guo, Jiancai Li, Jin Zhang, Li Chen, Manqun Wang, Michele Ricupero, Peng Han, Peng He, Qi Yan, Qingbo Tang, Qingsong Liu, Shiheng An, Xiangbo Kong, Xiaoling Sun, Xueming Ren, Yuanyuan Song, Yang Liu, Yanhui Guo, Yunhe Li, Xiao Sun   +31 more
wiley   +1 more source

Morphological Seed Traits Predict Early Performance of Native Species to Pelletized Seed Enhancement Technologies. [PDF]

Plants (Basel)
Andres SE, Lieurance PE, Mills CH, Tetu SG, Gallagher RV.   +4 more
europepmc   +1 more source

Engineering Approaches to Modify Immunomodulatory Functions of Mesenchymal Stromal Cells (MSCs): Tissue Regeneration and Clinical Application

Advanced Science, EarlyView.
Mesenchymal stromal cells (MSCs) show promise for treating immune‐related disorders through immunomodulation and tissue regeneration. This review gives a brief overview of current clinical approval of MSC therapies. It also discussed how bioengineering, including genetic modification, biomaterial delivery, extracellular vesicles, and iPSC‐derived MSCs,
Sichen Yang, Kejia Li, Ning Wang, Zhen Li, Zhiyong Zhang, Rocky S. Tuan, Yangzi Jiang   +6 more
wiley   +1 more source

Global disruption of plant biogeography by non-native species

Cai L, Weigelt P, Kreft H, Bruelheide H, Davis AJ, Dawson W, Essl F, van Kleunen M, Kühn I, Lenzner B, Pergl J, Pyšek P, Pelser PB, Wieringa JJ, Winter M.   +14 more
europepmc   +1 more source

¹¹C-Labeling of a Flavanone Extracted from a South American Native Species for Evaluation of Its Interaction with GSK-3β. [PDF]

Molecules
Zeni M, Santi MD, Arredondo F, Reyes L, Bentura M, Carvalho D, Peralta M, Ortega MG, Abin-Carriquiry JA, Martínez-Gonzalez L, Gambini JP, Duarte P, Martinez A, Martinez A, Rey A, Giglio J.   +15 more
europepmc   +1 more source