Results 61 to 70 of about 1,418,943 (330)

The epithelial barrier theory proposes a comprehensive explanation for the origins of allergic and other chronic noncommunicable diseases

FEBS Letters, EarlyView.
Exposure to common noxious agents (1), including allergens, pollutants, and micro‐nanoplastics, can cause epithelial barrier damage (2) in our body's protective linings. This may trigger an immune response to our microbiome (3). The epithelial barrier theory explains how this process can lead to chronic noncommunicable diseases (4) affecting organs ...
Can Zeyneloglu, Huseyn Babayev, Ismail Ogulur, Sena Ardicli, Yagiz Pat, Duygu Yazici, Bingjie Zhao, Lihong Chang, Xiaoqing Liu, Paolo D'Avino, Manru Li, Ceren Biçer, Fatma Hacer Kurtoğlu Babayev, Raja Dhir, Kari C. Nadeau, Marie‐Charlotte Brüggen, Mubeccel Akdis, Cezmi A. Akdis   +17 more
wiley   +1 more source

Goodbye flat lymphoma biology

FEBS Letters, EarlyView.
Three‐dimensional (3D) biological systems have become key tools in lymphoma research, offering reliable in vitro and ex vivo platforms to explore pathogenesis and support precision medicine. This review highlights current 3D non‐Hodgkin lymphoma models, detailing their features, advantages, and limitations, and provides a broad perspective on future ...
Carla Faria, Cèlia Dobaño‐López, Patricia Pérez‐Galán, Christine Bezombes   +3 more
wiley   +1 more source

Grassland songbird abundance is influenced more strongly by individual types of disturbances than cumulative disturbances associated with natural gas extraction.

PLoS ONE, 2023
Grassland birds have undergone widespread global population declines due to loss and degradation of native grasslands. Activities associated with non-renewable energy derived from oil and natural gas extraction have substantially increased on grasslands.
Stephen K Davis, Holly J Kalyn Bogard, David Anthony Kirk, Lauren Moretto, R Mark Brigham   +4 more
doaj   +1 more source

From omics to AI—mapping the pathogenic pathways in type 2 diabetes

FEBS Letters, EarlyView.
Integrating multi‐omics data with AI‐based modelling (unsupervised and supervised machine learning) identify optimal patient clusters, informing AI‐driven accurate risk stratification. Digital twins simulate individual trajectories in real time, guiding precision medicine by matching patients to targeted therapies.
Siobhán O'Sullivan, Lu Qi, Pierre Zalloua   +2 more
wiley   +1 more source

Exploring lipid diversity and minimalism to define membrane requirements for synthetic cells

FEBS Letters, EarlyView.
Designing the lipid membrane of synthetic cells is a complex task, in which its various roles (among them solute transport, membrane protein support, and self‐replication) should all be integrated. In this review, we report the latest top‐down and bottom‐up advances and discuss compatibility and complexity issues of current engineering approaches ...
Sergiy Gan, Victoria Scarpelli, Marten Exterkate   +2 more
wiley   +1 more source

Diversity and abundance of phosphonate biosynthetic genes in nature [PDF]

Proceedings of the National Academy of Sciences, 2013
Significance Phosphonic acids are organophosphorus molecules containing direct carbon–phosphorus bonds that are often perceived as biological rarities. The data presented here show that the ability to synthesize diverse phosphonates is both widespread and relatively common among microbes.
Yu, Xiaomin, Doroghazi, James R., Janga, Sarath Chandra, Zhang, Jun Kai, Circello, Benjamin, Griffin, Benjamin M., Labeda, David P., Metcalf, William W.   +7 more
openaire   +3 more sources

Tree regeneration responds more to shade casting by the overstorey and competition in the understorey than to abundance per se [PDF]

, 2019
Manipulating the overstorey is the key tool for forest managers to steer natural regeneration. Opening up the canopy does not only create favourable light conditions for tree seedling growth, but also for (competitive) understorey species.
Baeten, Lander, De Lombaerde, Emiel, Van Calster, Hans, Verheyen, Kris   +3 more
core   +1 more source

Ergothioneine supplementation improves pup phenotype and survival in a murine model of spinal muscular atrophy

FEBS Letters, EarlyView.
Spinal muscular atrophy (SMA) is a genetic disease affecting motor neurons. Individuals with SMA experience mitochondrial dysfunction and oxidative stress. The aim of the study was to investigate the effect of an antioxidant and neuroprotective substance, ergothioneine (ERGO), on an SMNΔ7 mouse model of SMA.
Francesca Cadile, Daniela Ratto, Giorgia Rastelli, Ottavia Eleonora Ferraro, Caterina Temporini, Sunil Kumar, Simona Boncompagni, Paola Rossi, Monica Canepari   +8 more
wiley   +1 more source

Use of N Natural Abundance and N Species Concentrations to Assess N-Cycling in Constructed and Natural Coastal Wetlands

Applied and Environmental Soil Science, 2010
Natural abundance of N stable isotopes used in combination with concentrations may be useful indicators of N-cycling in wetlands. Concentrations and N signatures of NO3−, NH4+, and sediment organic nitrogen (SON) were measured in two impacted coastal ...
C. Marjorie Aelion, Melissa R. Engle, Hongbo Ma   +2 more
doaj   +1 more source

Energy: Natural limits and abundances

Eos, Transactions American Geophysical Union, 1974
With the decline of ancient civilization—the successive incinerations of the great Library of Alexandria in the fourth century and the Moslem conquest of Egypt in the seventh—it remained for Persian and Arabian scholars to assemble, record, and continue to enlarge knowledge.
openaire   +2 more sources