Results 151 to 160 of about 5,284,025 (257)

HELIN Circulation Committee minutes for 5/1/02

open access: yes, 2002
Minutes of the Circulation Committee of the HELIN Consortium for May ...
HELIN Consortium. Circulation Committee
core  

Thymosin Alpha‐1 Provides Direct Neuroprotection by Engaging the Orexin Receptor HCRTR1 to Suppress Neuronal Necroptosis

open access: yesAdvanced Science, EarlyView.
In this study, we unveil a thymus‐brain endocrine axis wherein Tα1 engages HCRTR1 to inhibit RIPK3‐mediated necroptosis. This study nominates the Tal‐HCRTR1‐RIPK3 axis as a potent and clinically translatable therapeutic target for stroke and neurodegeneration.
Xinmei Kang   +11 more
wiley   +1 more source

HELIN Circulation Committee minutes for 7/12/00

open access: yes, 2000
Minutes of the Circulation committee of the HELIN Consortium for July ...
HELIN Consortium. Circulation Committee
core  

Chiral Nanoparticles Suppress Inflammatory Infiltration to Promote Extracellular Matrix Remodeling for Ectopia Lentis Therapy

open access: yesAdvanced Science, EarlyView.
L‐cysteine‐configured chiral polyurethane nanoparticles suppress ocular inflammation and reduce extracellular matrix (ECM) degradation in ectopia lentis by regulating macrophages polarization and inhibiting nuclear factor kappa B signaling pathway. By promoting zonular fiber‐associated protein restoration and tissue repair, this minimally invasive ...
Yinuo Wen   +17 more
wiley   +1 more source

HELIN Circulation Committee minutes for 10/07/98

open access: yes, 1998
Minutes of the Circulation Committee of the HELIN Consortium for October ...
HELIN Consortium. Circulation Committee
core  

TOLLIP Inhibits Psoriasis Progression via Suppressing PKM2‐Mediated Glycolysis in Keratinocytes

open access: yesAdvanced Science, EarlyView.
In this study, we identify TOLLIP as a critical regulator of psoriasis pathogenesis through its modulation of glycolytic metabolism. Our findings establish the TOLLIP‐PKM2‐glycolysis axis as a key mechanism linking metabolic reprogramming to psoriasis pathogenesis, and propose TOLLIP as a promising therapeutic target.
Xiuhuan Jiang   +11 more
wiley   +1 more source

HELIN Circulation Committee minutes for 8/15/01

open access: yes, 2001
Minutes of the Circulation committee of the HELIN Consortium for August ...
HELIN Consortium. Circulation Committee
core  

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