High glucose is linked to reduced succinate dehydrogenase activity in CD14+ monocytes, accompanied by succinate accumulation and extracellular release. Extracellular succinate exacerbates mitochondrial ROS production and mtDNA release in CD4+ T cells. Cytosolic mtDNA then activates Z‐DNA binding protein 1 (ZBP1) and engages ZBP1‐associated inflammatory
Shuai Zhao +11 more
wiley +1 more source
Natural disaster emergency response from a public policy perspective: a four-party evolutionary game among government, international organizations, healthcare institutions, and enterprises. [PDF]
Wu B +7 more
europepmc +1 more source
Paraborg: Paramedic Cyborg Insects for In Situ Emergency Drug‐Delivery
This work introduces Paraborg, a human‐supervised paramedic cyborg‐insect platform that combines controllable locomotion, onboard imaging, and an auto‐injection mechanism for in situ drug‐delivery. By demonstrating reliable navigation, target stabilization, injector launch, and multi‐insect teamwork, the study extends cyborg insects from survivor ...
H. Nhan Le +5 more
wiley +1 more source
Reproductive health crisis amidst a natural disaster in Pakistan: A call to action. [PDF]
Waseem S +4 more
europepmc +1 more source
Engineered macrophages programmed in situ by LNP‐delivered IL‐6/4 fusion and LL37 mRNAs simultaneously dampen cytokine storm, promote M2‐like repair, and enhance direct bacterial killing in sepsis. This combinatorial strategy restores T cell and macrophage function, lowers organ bacterial burden, and improves survival, highlighting a precision, host ...
Tianyang Jie +10 more
wiley +1 more source
Social Representations of Formal Volunteers and Spontaneous Volunteers in Socio-Natural Disaster Risk Management Contexts. [PDF]
Peña-Garay M +2 more
europepmc +1 more source
Bio‐Inspired Gradient Coatings Enhance the Leading Edge Erosion Resistance of Wind Blades
Rain‐induced erosion of the wind turbine blade leading edge poses a critical challenge to maintenance and operation. Here, we propose a bio‐inspired approach for erosion protection utilising a platelet‐reinforced polyurethane coating with a graded through‐thickness architecture.
Natalia Sofia Guevara‐Sotelo +2 more
wiley +1 more source
The measurement of rural community resilience to natural disaster in China. [PDF]
Li Y, Wang S, Zhang Y, Du G.
europepmc +1 more source
Battery‐Inspired Electrochemical Synapses for Neuromorphic Applications
Battery‐ion‐inspired synaptic devices integrate diverse electrolyte systems (solid, ion‐gel, liquid) with transition metal oxides, two‐dimensional materials, and organic channels to regulate ion‐electron coupling. By tailoring ion transport and host interactions, these platforms enable controllable plasticity and energy‐efficient implementations for ...
Won Woo Lee +6 more
wiley +1 more source
Understanding Natural Disaster or Weather-Related Drowning Deaths Among Children. [PDF]
Hillers GM +6 more
europepmc +1 more source

