Results 121 to 130 of about 490,565 (325)

Working as one: a road map to disaster resilience for Australia [PDF]

open access: yes, 2014
This report offers a roadmap for enhancing Australia’s disaster resilience, building on the 2011 National Strategy for Disaster Resilience. It includes a snapshot of relevant issues and current resilience efforts in Australia, outlining key challenges ...
Anthony Bergin   +2 more
core   +1 more source

NARFL Knockout Triggers Ferroptosis‐Driven Vascular Endothelial Dysfunction

open access: yesAdvanced Science, EarlyView.
NARFL is vital for CIA and oxidative stress resistance. NARFL deletion in HPMEC cells, zebrafish, and mice is lethal and rescued by a Ferroptosis inhibitor. NARFL deficiency disrupted its interaction with CIA proteins, decreased aconitase activity, increased IRP1 activity, induced Fe overload, and led to ferroptosis and oxidative stress, resulting in ...
Hui Hu   +15 more
wiley   +1 more source

Modifying Glucose Metabolism Reverses Memory Defects of Alzheimer's Disease Model at Late Stages

open access: yesAdvanced Science, EarlyView.
Using spatial transcriptomics, we show that ferul enanthate (SL‐ZF‐01) reverses episodic‐like memory deficits in aged, but not young, Alzheimer’s disease (AD) mice. SL restores glucose metabolism and Glucose Transporter 1/3 expression via an ‘Aging‐AD‐Rescue’ pattern, rescuing deficits seen in aged AD mice.
Fang Liu   +14 more
wiley   +1 more source

Machine learning reveals lithology and soil as critical parameters in landslide susceptibility for Petrópolis (Rio de Janeiro State, Brazil)

open access: yesNatural Hazards Research
Petrópolis, located in the mountainous region of Rio de Janeiro, Brazil, is frequently impacted by severe landslides, exacerbated by intense rainfall, steep topography, and unregulated urban growth.
Enner Alcântara   +4 more
doaj   +1 more source

Gut Bacteria Improve Depressive Symptoms by Degrading Cortisol into Androgen

open access: yesAdvanced Science, EarlyView.
Chronic stress is an important risk factor for stress‐related disorders such as depression. Stress hormone cortisol is essential for the pathogenesis of stress‐related disorders such as depression. Some gut microbiota degraded cortisol, and improve depressive symptoms.
Xiong Wang   +12 more
wiley   +1 more source

Ecosystem‐Centered Robot Design: Toward Ecoresorbable Sustainability Robots (ESRs)

open access: yesAdvanced Science, EarlyView.
Robots exploring natural ecosystems can support monitoring and conservation, but must adopt ecosystem‐centered design to avoid pollution, waste, and damage. This review proposes guidelines for co‐designing ecoresorbable sustainability robots (ESRs), uniting materials, robotics, and ecological contexts in a single framework.
Tülin Yılmaz Nayır   +4 more
wiley   +1 more source

Climate change-induced shifts in landslide susceptibility in São Sebastião (southeastern Brazil)

open access: yesNatural Hazards Research
Landslides are a pressing natural hazard, particularly in regions prone to extreme weather events, and their frequency is expected to rise due to climate change.
Enner Alcântara   +4 more
doaj   +1 more source

Mozambique and natural disasters: human capital under threat [PDF]

open access: yes
This paper assesses the effect of a sequence of natural disasters on children’s health that hit Mozambique at the start of the 21st Century. The disasters in question were the floods of 2000 and the droughts of the years 2002 and 2003.
Prado C. Alfaiate, Jorge
core   +1 more source

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