Multidisciplinary cutting-edge technologies accelerating target-based drug discovery. [PDF]
J Pharm AnalLi Y, Moaddel R, Jiang Z, Chen X.
europepmc +1 more source
Rank‐based estimation of propensity score weights via subclassification
Canadian Journal of Statistics, EarlyView.Abstract Propensity score (PS) weighting estimators are widely used for causal effect estimation and enjoy desirable theoretical properties, such as consistency and potential efficiency under correct model specification. However, their performance can degrade in practice due to sensitivity to PS model misspecification.
Linbo Wang +3 more
wiley +1 more source
Heritability of early seedling growth in Taxus baccata, a declining conifer. [PDF]
Sci RepChybicki IJ +3 more
europepmc +1 more source
Hidden Markov graphical models with state‐dependent generalized hyperbolic distributions
Canadian Journal of Statistics, EarlyView.Abstract In this article, we develop a novel hidden Markov graphical model to investigate time‐varying interconnectedness between different financial markets. To identify conditional correlation structures under varying market conditions and accommodate shape features embedded in financial time series, we rely upon the generalized hyperbolic family of ...
Beatrice Foroni +2 more
wiley +1 more source
<i>clpC</i>-Mediated Translational Control Orchestrates Stress Tolerance and Biofilm Formation in Milk-Originated <i>Staphylococcus aureus</i> RMSA24. [PDF]
FoodsZhang M, Hu J, Xue T.
europepmc +1 more source
Bayesian inverse ensemble forecasting for COVID‐19
Canadian Journal of Statistics, EarlyView.Abstract Variations in strains of COVID‐19 have a significant impact on the rate of surges and on the accuracy of forecasts of the epidemic dynamics. The primary goal for this article is to quantify the effects of varying strains of COVID‐19 on ensemble forecasts of individual “surges.” By modelling the disease dynamics with an SIR model, we solve the ...
Kimberly Kroetch, Don Estep
wiley +1 more source
Unifying non-Markovian dynamics and agent heterogeneity in scalable stochastic networks. [PDF]
Nat CommunPélissier A +4 more
europepmc +1 more source
Cytoskeleton, EarlyView.ABSTRACT Cells sense the stiffness of their extracellular matrix (ECM) and adapt their behavior accordingly. We investigated how ECM stiffness affects the spatial organization of talin1, a key mechanosensitive focal adhesion protein. Using polyacrylamide (PA) hydrogels with tunable stiffnesses (0.2–188 kPa), we analyzed cell morphology, migration ...
Joanna Hajduk +5 more
wiley +1 more source
Propagation of solitary waves for hydrodynamical nonlinear complex model in a fractional derivative setting. [PDF]
Sci RepBilal M +6 more
europepmc +1 more source
Invariant Measure and Universality of the 2D Yang–Mills Langevin Dynamic
Communications on Pure and Applied Mathematics, EarlyView.ABSTRACT We prove that the Yang–Mills (YM) measure for the trivial principal bundle over the two‐dimensional torus, with any connected, compact structure group, is invariant for the associated renormalised Langevin dynamic. Our argument relies on a combination of regularity structures, lattice gauge‐fixing and Bourgain's method for invariant measures ...
Ilya Chevyrev, Hao Shen
wiley +1 more source