Results 141 to 150 of about 7,944,445 (301)

The Aging Blood: Cellular Origins, Circulating Drivers, and Therapeutic Potential

Aging and Cancer, EarlyView.
As a conduit linking all organs, the blood system both reflects and actively drives systemic aging. This review highlights how circulating pro‐aging and antiaging factors and age‐associated hematopoietic stem cell dysfunction contribute to immunosenescence and multi‐organ decline, positioning the hematopoietic system as a target for aging intervention.
Hanqing He, Jianwei Wang
wiley   +1 more source

Natural Products as Geroprotective Modulators in Diabetic Nephropathy: A Mechanistic Framework Integrating Aging Hallmarks and the AMPK–SIRT1–Nrf2 Axis

Aging and Cancer, EarlyView.
Natural products target the aging kidney in diabetic nephropathy by restoring the AMPK–SIRT1–Nrf2 axis, reducing oxidative stress, inflammation, fibrosis, and cellular senescence while enhancing mitochondrial biogenesis and antioxidant defenses.
Sherif Hamidu, Latif Adams, Eunice Ampem‐Danso, Justice Kumi, Abigail Aning, Fatima Hamidu, Mustapha Abdul Mumin Mohammed, Ayuba Nii Darku Ankrah, Seth Kwabena Amponsah   +8 more
wiley   +1 more source

Burn permits need to facilitate – not prevent – “good fire” in California

California Agriculture, 2020
Robert A. York, Ariel Roughton, Ryan Tompkins, Susan Kocher   +3 more
doaj   +1 more source

Analysis of knowledge, attitude and behaviors of farmers regarding the safe use of pesticides and their health risks related experiences in Galogah county, Mazandaran province, Iran

سلامت و محیط, 2020
Background and Objective: pesticides are essential to protect plants from pests and diseases. Extensive and unsafe use of pesticides by farmers pose various risks to human health and the environment. Therefore, the present study evaluates farmerschr('39')
Mogheiseh Sherafati, Gholamhossein Abdollahzadeh, Mohammad Sharif Sharifzadeh, Mohammad Reza Mahboobi   +3 more
doaj  

Re‐Awakening Public Attention to the Silent Pandemic of Cancer Among Older Adults in Low‐ and Middle‐Income Countries

Aging and Cancer, EarlyView.
ABSTRACT As global populations age, cancer is increasingly becoming a leading cause of morbidity and mortality among older adults, particularly in low‐ and middle‐income countries (LMICs). Despite accounting for the majority of new cancer cases and deaths, older individuals remain underrepresented in cancer research, clinical guidelines, and health ...
Ibrahim Bidemi Abdullateef, Sunkanmi Folorunsho, Abdulazeez Opeyemi Abdulganiyu   +2 more
wiley   +1 more source

Tracking Motor Progression and Device‐Aided Therapy Eligibility in Parkinson's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To characterise the progression of motor symptoms and identify eligibility for device‐aided therapies in Parkinson's disease, using both the 5‐2‐1 criteria and a refined clinical definition, while examining differences across genetic subgroups.
David Ledingham, Sahana Sathyanarayana, Charlotte B. Stewart, Robyn Iredale, Victoria Foster, Debra Galley, Mark Baker, Nicola Pavese   +7 more
wiley   +1 more source

Cardioprotection and lifespan extension by the natural polyamine spermidine

Nature Medicine, 2016
T. Eisenberg, M. Abdellatif, Sabrina Schroeder, U. Primessnig, S. Stekovic, T. Pendl, A. Harger, J. Schipke, A. Zimmermann, A. Schmidt, Mingming Tong, C. Ruckenstuhl, Christopher Dammbrueck, A. Gross, V. Herbst, C. Magnes, G. Trausinger, Sophie H. Narath, A. Meinitzer, Zehan Hu, A. Kirsch, K. Eller, D. Carmona‐Gutierrez, S. Büttner, F. Pietrocola, Oskar Knittelfelder, Emilie Schrepfer, P. Rockenfeller, C. Simonini, A. Rahn, M. Horsch, K. Moreth, J. Beckers, H. Fuchs, V. Gailus-Durner, F. Neff, D. Janik, B. Rathkolb, J. Rozman, M. H. de Angelis, T. Moustafa, G. Haemmerle, M. Mayr, P. Willeit, Marion von Frieling-Salewsky, B. Pieske, L. Scorrano, T. Pieber, R. Pechlaner, J. Willeit, S. Sigrist, W. Linke, C. Mühlfeld, J. Sadoshima, J. Dengjel, S. Kiechl, G. Kroemer, S. Sedej, F. Madeo   +58 more
semanticscholar   +1 more source

Visual Recovery Reflects Cortical MeCP2 Sensitivity in Rett Syndrome

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Rett syndrome (RTT) is a devastating neurodevelopmental disorder with developmental regression affecting motor, sensory, and cognitive functions. Sensory disruptions contribute to the complex behavioral and cognitive difficulties and represent an important target for therapeutic interventions.
Alex Joseph Simon, Nathalie Picard, Valeria d'Andrea, Enchi Chang, Joseph Leffler, Eleonora Centofante, Matthew Taylor, Francesca Bardi, Francesca Cavicchiolo, Takao K. Hensch, Stefano Panzeri, Chinfei Chen, Michela Fagiolini   +12 more
wiley   +1 more source

Accelerated Progression of Gait Impairment in Parkinson's Disease and REM Sleep Without Atonia

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective People with Parkinson's disease (PD) and rapid eye movement (REM) sleep without atonia (RSWA) often have more severe gait disturbances compared to PD without RSWA. The association between the presence and expression of RSWA and the rate of progression of gait impairment in PD is unknown.
Sommer L. Amundsen‐Huffmaster, Jae Woo Chung, Maria E. Linn‐Evans, Matthew N. Petrucci, Chiahao Lu, Destiny J. Weaver, Joshua De Kam, Scott E. Cooper, Paul J. Tuite, Aleksandar Videnovic, Michael J. Howell, Colum D. MacKinnon   +11 more
wiley   +1 more source

Valuation of ecosystem services in Iranian protected forests: An economic approach to achieve sustainable development

Sustainable Futures
This study aims to assign economic value to ecosystem services within protected areas, ensuring that non-market services are not ignored and enabling a comparative analysis between market and non-market values.
Mehdi Zandebasiri, Hamzeh Ali Shirmardi, Kamal Ataie Solout, Zohreh Mosleh Ghahfarokhi, Mahmoud Talebi, Touraj Mokhtarpour   +5 more
doaj   +1 more source