Results 131 to 140 of about 131,765 (311)

Expanding Chemical Space of Nucleic Acid Nanoparticles for Tunable Antiviral‐Like Immunomodulatory Responses and Potent Adjuvant Activity

Advanced Functional Materials, EarlyView.
We introduce a nucleic acid nanoparticle (NANP) platform designed to be rrecognized by the human innate immune system in a regulated manner. By changing chemical composition while maintaining constant architectural parameters, we identify key determinants of immunorecognition enabling the rational design of NANPs with tunable immune activation profiles
Martin Panigaj, Hannah S. Newton, Jian Wang, Laxmi Pandey, Yelixza I. Avilla, Phong Nguyen, Morgan Chandler, Justin Halman, Yasmine Radwan, Stephanie Smith, Elijah Edmondson, Simone Difilippantonio, Chelsea Sanders, Bao Tran, Yongmei Zhao, Shaojun Xie, Edward Cedrone, Barry W. Neun, Meni Wanunu, Nikolay V. Dokholyan, Marina A. Dobrovolskaia, Kirill A. Afonin   +21 more
wiley   +1 more source

Comparative Analysis of Bacterial Tick-Borne Pathogens in Questing Ticks from Sambia Peninsula, Kaliningrad Oblast, Russia: Spring and Autumn Prevalence and Public Health Risks

Microorganisms
The Kaliningrad Oblast, located in the westernmost part of Russia and bordering European Union countries, is a popular tourist destination. However, limited research has been conducted on the bacteria found in ticks in this region.
Alexey V. Rakov, Evgenii G. Volchev, Ketevan Petremgvdlishvili, Tatiana A. Chekanova   +3 more
doaj   +1 more source

Assessment of the results of seromonitoring of natural focal infections using a database

Medical Herald of the South of Russia
Objective: is to analyze the effectiveness of the updated database of the serological monitoring on natural focal dis eases among healthy donors, which allows results accumulation and systematization in order to ensure sanitary and epidemio logical surveillance in the Rostov region.
A. V. Trishina, E. A. Bereznyak, N. L. Pichurina, Y. L. Bereznyak, E. Y. Lyukshina, O. A. Noskova, E. I. Glushchenko   +6 more
openaire   +2 more sources

Tailoring the Properties of Functional Materials With N‐Oxides

Advanced Functional Materials, EarlyView.
The properties of materials bearing N‐oxide groups are often dominated by the polar N+─O− bond. It provides hydrophilicity, selective ion‐binding, electric conductivity, or antifouling properties. Many of the underlying mechanisms have only recently been discovered, and the interest in N‐oxide materials is rapidly growing.
Timo Friedrich, Michelle Kobus, Shirin Mesgarha, Erica Moretto, Laurens Grosche, Wolfgang Maison   +5 more
wiley   +1 more source

Review of the Epidemiological Situation on Ixodidae Tick-Borne Borrelioses in the Russian Federation in 2010–2024 and Forecast for 2025

Проблемы особо опасных инфекций
The aim of the review was to characterize the epidemiological situation on Ixodidae tick-borne borreliosis (ITBB) in the constituent entities of the Russian Federation in 2024, to forecast the development of the ITBB epidemic process in 2025 based on the
S. A. Rudakova, O. E. Teslova, N. E. Mutalinova, N. V. Rudakov, N. A. Pen’evskaya, Yu. F. Kuz’menko, D. V. Trankvilevsky   +6 more
doaj   +1 more source

Serological monitoring of actual natural focal infections in the Rostov Region (2020–2022)

Medical Herald of the South of Russia
Objective: to study the level of the immune layer of the population to pathogens of natural focal infectious diseases in order to establish the epidemic activity of natural foci of particularly dangerous infectious diseases in the Rostov region.Materials and methods: blood serums of healthy donors living in the administrative territories of the region ...
E. A. Bereznyak, A. V. Trishina, N. L. Pichurina, L. A. Egiazaryan, I. R. Simonova, N. E. Gayevskay, F. V. Logvin, V. V. Batashev, A. K. Noskov   +8 more
openaire   +2 more sources

A Smart Bio‐Battery Facilitates Diabetic Bone Defect Repair Via Inducing Macrophage Reprogramming and Synergistically Modulating Bone Remodeling Coupling

Advanced Functional Materials, EarlyView.
This research presents a novel implantable bio‐battery, GF‐OsG, tailored for diabetic bone repair. GF‐OsG generates microcurrents in high‐glucose conditions to enhance vascularization, shift macrophages to the M2 phenotype, and regulate immune responses.
Nanning Lv, Haifu Sun, Wenxiang Tang, Yonggang Li, Zhonglai Qian, Lihui Hong, Chong Chen, Hongye Li, Jiaxiang Bai, Yusen Qiao, Mingming Liu   +10 more
wiley   +1 more source

Diagnosis and management of pneumonia in the emergency department. [PDF]

, 2008
Pneumonia is a condition that is often treated by emergency physicians. This article reviews the diagnosis and management of pneumonia in the emergency department and highlights dilemmas in diagnostic testing, use of blood and sputum cultures, hospital ...
Abrahamian, Fredrick M, Moran, Gregory J, Talan, David A   +2 more
core  

Epidemiological Situation on Vector-Borne Natural-Focal Infections in the Territory of Caucasian Mineral Waters

Problems of Particularly Dangerous Infections, 2014
Represented is the analysis of epidemiological situation on vector-borne natural-focal infections in the specially protected eco-resort territory of Russia - Caucasian Mineral Waters of the Stavropol Region. Climactic peculiarities of Caucasian Mineral Waters with their landscape diversity, high abundance rates of ticks and mosquitoes, and ...
N. F. Vasilenko, A. V. Ermakov, O. V. Maletskaya, A. N. Kulichenko   +3 more
openaire   +3 more sources

Programmable DNA‐Peptide Hybrid Nanostructures for Potent Neutralization of Multiple Influenza a Virus Subtypes

Advanced Functional Materials, EarlyView.
A multivalent antiviral platform based on honeycomb‐shaped DNA nanostructures (HC–Urumin) is developed to enhance the potency and breadth of the host defense peptide Urumin. Through spatially patterned trimeric presentation, HC–Urumin disrupts influenza A virus entry, improves cell viability, and reduces disease severity in vivo‐offering a modular and ...
Saurabh Umrao, Abhisek Dwivedy, Payton L. Haak, Dhanush Gandavadi, Laurie A. Rund, Chi Chen, Vineetha Mareddy, Lifeng Zhou, Jinwei Duan, Ying Fang, Andrew J. Steelman, Xing Wang   +11 more
wiley   +1 more source