Results 71 to 80 of about 130,596 (261)

Rising plasma nociceptin level during development of HCC: A case report [PDF]

, 2004
AIM: Although liver cirrhosis is a predisposing factor for hepatocellular carcinoma (HCC), relatively few reports are available on HCC in primary biliary cirrhosis.
Folhoffer, Anikó, Halász, Judit, Hantos, Mónika Beatrix, Horváth, Andrea, Illyés, György, Lakatos, Péter László, Schaff, Zsuzsa, Szalay, Ferenc, Tekes, Kornélia   +8 more
core   +1 more source

Mechanisms of IgE‐mediated food allergy and the role of allergen‐specific B cells

FEBS Letters, EarlyView.
Food allergy arises when allergen‐specific B cells preferentially produce immunoglobulin E (IgE) antibodies against harmless foods. This article explains the mechanisms driving IgE‐mediated reactions, highlights the central role of these B cells, and discusses how natural tolerance (NT) and oral immunotherapy (OIT) can reshape allergic immune responses.
Juan‐Felipe López, Özge Yilmaz Ardicli, Mübeccel Akdis   +2 more
wiley   +1 more source

Clinical and laboratory characteristics of tick-borne rickettsiosis related to Rickettsia sibirica and Candidatus Rickettsia tarasevichiae

Инфекция и иммунитет, 2022
The Siberian tick-borne typhus (STT) is the most common tick-borne rickettsiosis (TBR) in Russia, registered in 17 administrative territories of the Southern Siberia and the Far East.
N. V. Rudakov, I. E. Samoylenko, S. V. Shtrek, S. A. Rudakova, L. V. Kumpan, Ya. P. Igolkina, V. A. Rar, E. V. Zhirakovskaya, S. E. Tkachev, N. V. Tikunova, T. V. Kostrykina, I. A. Blokhina, P. A. Lents   +12 more
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Features of the Epidemic and Epizootic Situation on Rabies in the Russian Federation in 2023 in Comparison with Long-Term Data

Проблемы особо опасных инфекций
In the Russian Federation, a downward trend in animal rabies cases has been observed since 2008, and in human cases – since 2012. In 2023, the number of registered animal rabies cases (1082 ) was almost equal to the average indicator over the past 5 ...
E. M. Poleshchuk, E. S. Savkina, G. N. Sidorov   +2 more
doaj   +1 more source

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

Molecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee, Byung‐Cheol Han, Gi‐Bang Koo, Jihye Park, Mijin Kwon, Young Bin Park, Jae‐Mun Choi, Seung‐Ho Lee, Sangho Roh   +8 more
wiley   +1 more source

Epidemiological Situation on Rickettsial Diseases and Q Fever in the Russian Federation over the Period of 2010–2023, Forecast for 2024

Проблемы особо опасных инфекций
The aim of the review is to forecast the incidence of rickettsial infections and Q fever in the Russian Federation for 2024 based on an analysis of the epidemiological situation in 2010–2023.
S. V. Shtrek, N. V. Rudakov, S. N. Shpynov, A. I. Blokh, D. V. Trankvilevsky, N. A. Pen’evskaya, L. V. Kumpan, A. V. Sannikov   +7 more
doaj   +1 more source

Retrospective Evaluation of Implementation of Long-Term Forecast on Spatial Spread of Rabies in the Asian Part of Russia

Проблемы особо опасных инфекций, 2020
Objective: To evaluate the historical long-term forecast of the spatial spread of rabies in Siberia and Far East and to characterize modern approaches to spatial forecasting.
A. D. Botvinkin, G. N. Sidorov, E. M. Poleshchuk, L. D. Zarva, D. N. Nashatyreva, N. V. Yakovchits, E. I. Andaev, S. V. Balakhonov, N. V. Rudakov   +8 more
doaj   +1 more source

Intestinal transplantation [PDF]

, 1994
Intestinal transplantation is often the only alternative form of treatment for patients dependent on total parenteral nutrition for survival.
Andreas G. Tzakis, M.D, Deltz E, Murase N, Satoru Todo, M.D, Starzl TE, Starzl TE, Starzl TE, Thomas E. Starzl, M.D., Ph.D, Todo S, Tzakis AG   +9 more
core   +1 more source

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

FEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point, Wafaa Achache, Janïs Laudouze, Eliana Sepulveda Ramos, Mickaël Maziero, Céline Crauste, Stéphane Canaan, Pierre Santucci   +7 more
wiley   +1 more source