Results 121 to 130 of about 6,455,723 (294)

A Biofabricated Human Acinus‐on‐a‐Chip Unveils Mechanotransductive Drivers of Ventilator‐Induced Lung Injury via Decoupling Volutrauma and Barotrauma

open access: yesAdvanced Science, EarlyView.
This bioinspired acinus‐on‐a‐chip recapitulates VILI pathology, revealing that volutrauma drives P53/NF‐κB pathways while barotrauma triggers mitochondrial‐Wnt dysregulation. A fibrotic transitional cell cluster was identified. Pharmacological interventions targeting these pathways significantly ameliorated injury, establishing a mechanobiological ...
Heng Lu   +10 more
wiley   +1 more source

Natural Gas Pipeline Company of America, docket no. CP72-233, Sabine Pass Project.

open access: yes, 1973
91 p.The administrative action here involved arises from an application filed by Natural Gas Pipeline Company of America (Natural) seeking authorization pursuant to Section 7 of the Natural Gas Act for a certificate of public convenience and necessity ...
U.S. Federal Power Commission, Bureau of Natural Gas
core   +1 more source

Programming Gut Microbiome Function Through Cross‐Feeding: From Ecological Mechanisms to Live Biotherapeutics

open access: yesAdvanced Science, EarlyView.
This graphical abstract presents gut microbial cross‐feeding through a Mechanism–Technology–Application framework. It summarizes major resource‐transfer modes, the experimental and computational tools used to establish causality, and potential interventions involving dietary substrates, live biotherapeutic products, and engineered microbes.
Chuankai Sun   +7 more
wiley   +1 more source

Translational Barriers and AI‐Driven Challenges of Microfluidics‐Enabled Wearables and Implantable Systems in Personalized Medicine

open access: yesAdvanced Science, EarlyView.
An integrative review of microfluidics‐enabled wearables and implantable systems reveals a single‐track translation pipeline, bridging functional biomaterials with clinical utility. Dynamic feedback loops driven by artificial intelligence advance diagnostics toward personalized closed‐loop theranostics.
Ke Huang   +3 more
wiley   +1 more source

Cavity‐Enhanced Eye‐Readable Detection of 0.1% H2 via Active Modulation of Charge‐Transfer Plasmons

open access: yesAdvanced Science, EarlyView.
A cavity‐structured nanoparticle sensor is developed for highly sensitive, eye‐readable hydrogen detection. Its excellent colorimetric response arises from a hydrogen‐induced charge‐transfer mechanism: reduction of the dielectric oxide shell in H2 triggers a transition from the plasmonic gap mode to the charge‐transfer plasmon mode.
Xuemin Zhang   +9 more
wiley   +1 more source

Targeting LDHA Palmitoylation Sensitizes GBM to Chemoradiotherapy via Suppressing Palmitic Acid Induced Glycolytic Reprogramming

open access: yesAdvanced Science, EarlyView.
Mesenchymal GSCs preferentially uptake palmitic acid, thereby promoting ZDHHC12‐mediated LDHA palmitoylation. This modification enhances LDHA enzymatic activity, drives glycolytic reprogramming, and facilitates exosomal LDHA‐mediated TAM regulation.
Zijie Gao   +20 more
wiley   +1 more source

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