Results 221 to 230 of about 5,416,756 (285)

An explainable machine learning approach to predicting carbapenem resistance in <i>Klebsiella pneumoniae</i> with imbalanced data and resistance-ratio validation. [PDF]

Front Cell Infect Microbiol
Geng L, He Y, Yang G, Zheng S, Zhao L, Wang Q.   +5 more
europepmc   +1 more source

Predicting Enzyme Turnover Numbers and Enabling Rational Enzyme Evolution

Advanced Science, EarlyView.
MCKcat, a deep learning framework combining multi‐scale convolution and cross‐attention, accurately predicts enzyme turnover number (kcat) by fusing sequence and reaction representations. It couples with rational design in a two‐step strategy for Bacillus aryabhattai laccase engineering, achieving a 75% positive rate with synergistically enhanced ...
Fengya Ge, Xiangyang Ma, Jiyan Li, Mengxiang Wang, Fuping Lu, Yihan Liu, Lin Wang   +6 more
wiley   +1 more source

Estimating Individualized Survival Benefit of Consolidative Metastasis-Directed Radiotherapy Following Chemoimmunotherapy in Nasopharyngeal Carcinoma With Exclusive Distant Metastasis. [PDF]

MedComm (2020)
Wang X, Chen S, Zhang X, Mao L, Chen J, Yan S, Xie J, Gao X, Zheng L, Zeng Y, Zhang S, Deng Z, Du M, Song M.   +13 more
europepmc   +1 more source

Smart Bioinks for 4D Bioprinting: Requirements, Design, and Applications

Advanced Science, EarlyView.
Smart bioinks empower 4D‐bioprinted constructs to dynamically adapt and remodel in response to stimuli, effectively biomimicking native tissues. Artificial Intelligence (AI) and Machine Learning (ML) play a guiding role in their rational design by optimizing relevant properties.
Shangsi Chen, Jiahui Lai, Qiongjiao Zeng, Liangbin Zhou, Boguang Yang, Bin Zhang, Min Wang, Jiajing Zhou, Kieran Lau, Khoon S. Lim, Zhong Alan Li, Rocky S. Tuan   +11 more
wiley   +1 more source

Interpretable Machine Learning Model for Fungal Infection Prediction: A Real-World Study. [PDF]

Health Care Sci
Yang J, Pan S, Luo T, Zhang B, Feng B, Wang Y.   +5 more
europepmc   +1 more source

Self‐Healing Ionogel Dual‐Network Enables Synergistic Defect Passivation and Strain Relief for High‐Efficiency Robust Perovskite Photovoltaics

Advanced Science, EarlyView.
PSCs are afflicted by inherent defects and lattice strain that limit PCE and stability. A cross‐linked multifunctional ionogel [HA‐AA][EMIES] is developed to modulate crystallization, relieve residual strain, and passivate defects, extending carrier diffusion length to over 8 µm and delivering PCEs of 26.45% for rigid devices and 25.14% for flexible ...
Wen Wu, Gang Wang, Chen Liu, Xiao‐Li Du, Sheng Yang, Shao‐Long Wang, Jia‐Yi Tian, Ling‐Feng Chao, Xiang‐Feng Deng, Yi Jiang, Yong‐Hua Chen, Gui‐Chuan Xing, Wen‐Yong Lai   +12 more
wiley   +1 more source

Epidemiological Characteristics and Incidence Trends of Hemorrhagic Fever With Renal Syndrome in Shandong Province, China: Retrospective Observational Study With Forecasting. [PDF]

JMIR Public Health Surveill
Duan Q, Liu T, Li Y, Guo S, Huang S, Xu J, Li R, Kou Z.   +7 more
europepmc   +1 more source

Acid‐Responsive Nanobot‐Integrated Core‐Shell Microneedles Reprogram the Degenerative Annulus Fibrosus Microenvironment Through Epigenetic Suppression of Ferroptosis

Advanced Science, EarlyView.
An acid‐responsive core‐shell microneedle system normalizes the degenerative annulus fibrosus microenvironment by consuming pathological H+, generating O2, and providing NIR‐amplified redox buffering. Mechanistically, it epigenetically suppresses ferroptosis via DNMT3A‐dependent methylation of the ATF3 promoter, relieving ATF3‐mediated repression of ...
Lu Tan, Yan Zheng, Yue Lan, Zhuo Cheng, Siya Wang, Changqing Li, Yanqiu Wang, Minghan Liu   +7 more
wiley   +1 more source

Machine Learning-Based Prediction of Major Postoperative Complications After Noncardiac Surgery Under General Anesthesia Using Routinely Available Electronic Health Record Data: Retrospective Multicenter Development and Validation Study. [PDF]

JMIR Perioper Med
Nishino T, Mase H, Kim C, Sugita S, Kondo Y, Ishikawa M.   +5 more
europepmc   +1 more source