Results 141 to 150 of about 1,580,667 (265)

Re‐Purposing Sapropterin (Kuvan) for ACTA2‐Related Multisystemic Smooth Muscle Dysfunction Syndrome: A Translational Mechanistic and First‐In‐Human Therapeutic Report

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Multisystemic smooth muscle dysfunction syndrome (MSMDS) is an ultra‐rare, ACTA2‐related disorder characterized by severe cerebrovascular disease, aortic aneurysms, and smooth muscle dysfunction. Using molecular dynamics simulations and in silico drug screening, we identified that sapropterin dihydrochloride (Kuvan) is a candidate capable of ...
Moran Hausman‐Kedem, Noa Bielopolski, Vijai Krishnan, Shane Wald‐Altman, Shelly I Shrian, Omer Bar‐Yosef, Livia Kapusta, Claire Shamber, Patricia L. Musolino, Miguel Weil   +9 more
wiley   +1 more source

Impacts of dietary different doses of Polygonatum odoratum (Mill.) Druce fibrous root powder as a natural growth promoter on growth performance, carcass characteristics, meat quality and intestinal health of broilers. [PDF]

Poult Sci
Zhang L, Sun S, Tan J, Dong Z, Hu Y, Mi X, Zhang Q, Xiang W, Zeng J, Xie H.   +9 more
europepmc   +1 more source

Marked Long‐Term Improvement in Lung Function in Melanoma Differentiation–Associated Protein 5 Antibody–Positive Dermatomyositis Patients: Experience of a Single‐Center Longitudinal Cohort in North America

Arthritis Care &Research, EarlyView.
Objective The objective of this study was to describe the longitudinal disease course and pulmonary outcomes of North American patients with melanoma differentiation–associated protein 5 (MDA5) antibody–associated dermatomyositis (DM). Methods Thirty patients with MDA5 antibody–associated DM were identified in a single‐center longitudinal cohort of 352
Jenice X. Cheah, Sangmee S. Bae, Tiffany De Leon, Yuna Lee, Rong Guo, David Elashoff, Jennifer Wang, Ani Shahbazian, Christina Charles‐Schoeman   +8 more
wiley   +1 more source

Growth, Carcass Traits, Blood Chemistry and Gut Microbiota in Broiler Chickens Fed Diets Enriched With Garden Cress Seed Powder as a Natural Growth Enhancer. [PDF]

Vet Med Sci
Negm MH, Aldhalmi AK, Ashour EA, Mohamed LA, Kamal M, Rashad A, Khan MMH, Abd El-Hack ME, Swelum AA.   +8 more
europepmc   +1 more source

The Natural Growth Rate of Residual Juvenile Angiofibroma. [PDF]

J Neurol Surg B Skull Base, 2018
Rowan NR, Stapleton AL, Heft-Neal ME, Gardner PA, Snyderman CH.   +4 more
europepmc   +1 more source

Anorectal Dysfunction in Systemic Sclerosis: Clinical Phenotypes and Functional Patterns

Arthritis Care &Research, EarlyView.
Objective The aim of this study was to characterize specific physiologic defects in anorectal dysfunction in systemic sclerosis (SSc) using anorectal manometry (ARM), evaluate associations with gastrointestinal (GI) and extraintestinal clinical phenotypes, and explore potential serologic markers for risk stratification.
Timothy Kaniecki, Alireza Amindarolzarbi, Tsion Abdi, John Clarke, Michael Hughes, Ami A. Shah, Zsuzsanna H. McMahan   +6 more
wiley   +1 more source

Optimizing broiler performance, carcass traits, and health: evaluating thyme and/or garlic powders as natural growth promoters in antibiotic-free diets. [PDF]

Poult Sci
Ashour EA, Aldhalmi AK, Elolimy AA, Madkour M, Elsherbeni AI, Alqhtani AH, Khan IM, Swelum AA.   +7 more
europepmc   +1 more source

Observer‐Based Adaptive Event‐Triggered Tracking Control for Fuzzy TS Systems With Premise Mismatch

International Journal of Adaptive Control and Signal Processing, EarlyView.
This paper presents an adaptive logistic event‐triggered observer‐based tracking controller for Takagi‐Sugeno fuzzy systems under constrained inputs and network delays. Leveraging a hybrid LMI and Secretary Bird Optimization approach, this strategy significantly minimizes communication overhead and computational burden while ensuring optimal reference ...
Oussama Djadane, Salama Makni, Mourad Kchaou, Ahmed El Hajjaji   +3 more
wiley   +1 more source

Quantifying the natural growth rate of hepatocellular carcinoma: A real-world retrospective study in southwestern China. [PDF]

World J Hepatol
Tu L, Xie H, Li Q, Lei PG, Zhao PL, Yang F, Gong C, Yao YL, Zhou S.   +8 more
europepmc   +1 more source

Posterior cranial base natural growth and development: A systematic review. [PDF]

Angle Orthod, 2017
Currie K, Sawchuk D, Saltaji H, Oh H, Flores-Mir C, Lagravere M.   +5 more
europepmc   +1 more source