Results 51 to 60 of about 11,377,445 (319)
Insights into PI3K/AKT signaling in B cell development and chronic lymphocytic leukemia
This Review explores how the phosphoinositide 3‐kinase and protein kinase B pathway shapes B cell development and drives chronic lymphocytic leukemia, a common blood cancer. It examines how signaling levels affect disease progression, addresses treatment challenges, and introduces novel experimental strategies to improve therapies and patient outcomes.
Maike Buchner
wiley +1 more source
Characterization of fungal carbonyl sulfide hydrolase belonging to clade D β‐carbonic anhydrase
Here, we performed a functional analysis of the fungal enzymes belonging to clade D of the β‐class carbonic anhydrase family (β‐D‐CA). The β‐D‐CAs in the basidiomycete Gloeophyllum trabeum and the ascomycete Trichoderma harzianum showed very low activity in the hydration of CO2 but exhibited high activity in the hydrolysis of carbonyl sulfide (COS ...
Ryuka Iizuka+6 more
wiley +1 more source
Initial states and decoherence of histories [PDF]
We study decoherence properties of arbitrarily long histories constructed from a fixed projective partition of a finite dimensional Hilbert space. We show that decoherence of such histories for all initial states that are naturally induced by the projective partition implies decoherence for arbitrary initial states. In addition we generalize the simple
arxiv +1 more source
Size, microhabitat, and loss of larval feeding drive cranial diversification in frogs
The evolution of metamorphic species may be constrained by different ecologies of the larval and adult stages. Here, Bardua et al. show that in frogs, adult ecology is more important than larval ecology for skull evolution, but species that don’t feed as
Carla Bardua+7 more
doaj +1 more source
Epidemiology, Pathophysiology, and Natural History of Pulmonary Embolism
Pulmonary embolism (PE) is a common and potentially deadly form of venous thromboembolic disease. It is the third most common cause of cardiovascular death and is associated with multiple inherited and acquired risk factors as well as advanced age.
M. Turetz+4 more
semanticscholar +1 more source
In modular polyketide synthases, the dehydratase (DH) domain catalyzes the dehydration reaction of the β‐hydroxyacyl unit attached to the cognate acyl carrier protein (ACP) domain. However, it is unclear how DH interacts with ACP during the reaction. In this study, we identified DH–ACP interface residues, providing the first detailed insights into DH ...
Kaede Kotagiri+8 more
wiley +1 more source
Bulletin of the British Museum (Natural History). [PDF]
v.18:no.4 (1988:Oct.
British Museum (Natural History)
core +4 more sources
ZoologyCon 2024 - Book of Abstracts [PDF]
The book contains the abstracts and program of the international zoological congress ZOOLOGYCON 2024, organized by the Grigore Antipa Museum and held in Bucharest, Romania from 6th to 9th November 2024.
Luis Ovidiu Popa+12 more
doaj +3 more sources