Results 71 to 80 of about 4,890,231 (320)

The 1935 Hsinchu-Taichung Earthquake [PDF]

open access: yes, 2020
The history of natural disasters in Taiwan has frequently been linked to the practice of historical preservation, archival science, oral history, and museum curatorship.
Alsford, Niki J.P.
core   +2 more sources

Cell wall target fragment discovery using a low‐cost, minimal fragment library

open access: yesFEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan   +5 more
wiley   +1 more source

Approaches to estimating the universe of natural history collections data [PDF]

open access: yes, 2010
This contribution explores the problem of recognizing and measuring the universe of specimen-level data existing in Natural History Collections around the world, in absence of a complete, world-wide census or register. Estimates of size seem necessary to
Ariño, Arturo H.
core   +4 more sources

Nicotinamide N‐methyltransferase promotes drug resistance in lung cancer, as revealed by nascent proteomic profiling

open access: yesMolecular Oncology, EarlyView.
AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou   +5 more
wiley   +1 more source

The utility of micro-computed tomography for the non-destructive study of eye microstructure in snails

open access: yesScientific Reports, 2019
Molluscan eyes exhibit an enormous range of morphological variation, ranging from tiny pigment-cup eyes in limpets, compound eyes in ark clams and pinhole eyes in Nautilus, through to concave mirror eyes in scallops and the large camera-type eyes of the ...
Lauren Sumner-Rooney   +3 more
doaj   +1 more source

INHS Reports, Autumn 2006 [PDF]

open access: yes, 2006
Cache River Watershed | INHS Research Assists Restoration Efforts in the Cache River Watershed | Warblers Provide Link Between Behavioral Ecology and Conservation Biology | Molecular Phylogeny of Cuerna Leafhoppers Suggest Hybridization | A Cache Full of
Illinois Natural History Survey
core  

Investigating the cell of origin and novel molecular targets in Merkel cell carcinoma: a historic misnomer

open access: yesMolecular Oncology, EarlyView.
This study indicates that Merkel cell carcinoma (MCC) does not originate from Merkel cells, and identifies gene, protein & cellular expression of immune‐linked and neuroendocrine markers in primary and metastatic Merkel cell carcinoma (MCC) tumor samples, linked to Merkel cell polyomavirus (MCPyV) status, with enrichment of B‐cell and other immune cell
Richie Jeremian   +10 more
wiley   +1 more source

Screening for lung cancer: A systematic review of overdiagnosis and its implications

open access: yesMolecular Oncology, EarlyView.
Low‐dose computed tomography (CT) screening for lung cancer may increase overdiagnosis compared to no screening, though the risk is likely low versus chest X‐ray. Our review of 8 trials (84 660 participants) shows added costs. Further research with strict adherence to modern nodule management strategies may help determine the extent to which ...
Fiorella Karina Fernández‐Sáenz   +12 more
wiley   +1 more source

Natural History of Acute Subdural Hematoma [PDF]

open access: yes, 2017
Although guidelines for surgical decision-making in patients with acute subdural hematomas (ASDHs) are widely available, the evidence supporting these guidelines is weak, and management of these patients must often be individualized.
Valadka, Alex B., Vega, Rafael A.
core   +2 more sources

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