Results 141 to 150 of about 859,723 (353)

Positive feedback loop between MAPK and aquaporin 7 regulates autophagy and apoptosis induced by palmitate in RIN‐m5f cells

FEBS Open Bio, EarlyView.
T2DM is characterized by peripheral blood insulin resistance and progressive pancreatic β‐cell dysfunction. Here, we showed that AQP7, the only aquaglyceroporin protein, regulates autophagy and apoptosis in pancreatic β‐cells. We propose the existence of a positive feedback loop between MAPK signaling and AQP7 that regulates autophagy and apoptosis in ...
Maoqi Wang, Jiang Tan, Xueting He, Yuqin Chen, Guoping Qiu, Mei Yang   +5 more
wiley   +1 more source

Distribution and taxonomy of two closely related Nychiodes species in southern Italy (Lepidoptera, Geometridae, Ennominae) [PDF]

Nota Lepidopterologica
We investigated the distribution and species circumscription of Nychiodes obscuraria Villers (1789) and Nychiodes ragusaria Millière (1884). The morphology of male and female genitalia of Calabrian populations (southern Italy) revealed them to belong to ...
Ilaria Latella, Stefano Scalercio, Axel Hausmann   +2 more
doaj   +3 more sources

Bioengineering facets of the tumor microenvironment in 3D tumor models: insights into cellular, biophysical and biochemical interactions

FEBS Open Bio, EarlyView.
The tumor microenvironment is a dynamic, multifaceted complex system of interdependent cellular, biochemical, and biophysical components. Three‐dimensional in vitro models of the tumor microenvironment enable a better understanding of these interactions and their impact on cancer progression and therapeutic resistance.
Salma T. Rafik, Deniz Bakkalci, Alexander J. MacRobert, Umber Cheema   +3 more
wiley   +1 more source

Some Chernetid Pesudoscorpions from Mexico [PDF]

, 1953
Included in the collection of chernetid pseudoscorpions from the American Museum of Natural History were found several individuals representing the species and records described herein as new.
Neuberger, Harold T.
core   +1 more source

Snagged setae: evaluating alternatives to cotton wool bungs for liquid-stored specimens [PDF]

, 2018
Society for the Preservation of Natural History Collections Copyright © 2018. All rights reserved. Article is available as open access.
Allington-Jones, L, Sherlock, E
core   +1 more source

Hydrophobicity causes anomalous migration of cystine/glutamate antiporter SLC7A11 in SDS‐PAGE with low acrylamide concentration

FEBS Open Bio, EarlyView.
SLC7A11 frequently migrates faster in SDS‐PAGE. The present study found that the high hydrophobicity of SLC7A11 causes its anomalous migration in SDS‐PAGE with a low concentration of acrylamide gel. Replacing isoleucine with asparagine reduced hydrophobicity and restored its normal migration at 55 kDa, revealing the role of hydrophobicity and gel ...
Nsengiyumva Emmanuel, Qian He, Yixin Kang, Dianbao Zhang, Min Gao, Minglin Wang, Kexin Fan, Jingwen Xiong, Shaobo Wu, Botao Fa, Zhengtao Xiao, Yingfang Niu, Jun Yao, Yilei Zhang   +13 more
wiley   +1 more source

Developing the Protocol Infrastructure for DNA Sequencing Natural History Collections. [PDF]

Biodivers Data J, 2023
Ferrari G, Esselens L, Hart ML, Janssens S, Kidner C, Mascarello M, Peñalba JV, Pezzini F, von Rintelen T, Sonet G, Vangestel C, Virgilio M, Hollingsworth PM.   +12 more
europepmc   +1 more source

Nature's Book Keeping System [PDF]

arXiv, 2016
Establishing how one should describe and study natures fundamental degrees of freedom is a notoriously difficult problem. It is tempting to assume that the number of bits (or qubits) needed in a given Planckian 3-volume, or perhaps 2-volume, is a fixed finite number, but this ansatz does not make the problem much easier.
arxiv  

Nuevas especies de Alucitidae de la República de Suráfrica (Lepidoptera: Alucitidae) [PDF]

, 2021
According to the materials examined in the collections of the Natural History Museum in Pretoria (Republic of South Africa) and collections of the authors, we describe two new species of Alucitidae from Republic of South Africa: Alucita hendriki ...
Kovtunovich, Vasiliy N., Streltzov, Alexander N., Ustjuzhanin, Peter Ya., Ustjuzhanina, Anna K.   +3 more
core   +1 more source

METTL3 knockout accelerates hepatocarcinogenesis via inhibiting endoplasmic reticulum stress response

FEBS Open Bio, EarlyView.
Liver‐specific knockout of N6‐methyladenosine (m6A) methyltransferase METTL3 significantly accelerated hepatic tumor initiation under various oncogenic challenges, contrary to the previously reported oncogenic role of METTL3 in liver cancer cell lines or xenograft models. Mechanistically, METTL3 deficiency reduced m6A deposition on Manf transcripts and
Bo Cui, Silin Tu, Haibo Li, Zhancheng Zeng, Ruiqi Xiao, Jing Guo, Xiaoqi Liang, Chang Liu, Lijie Pan, Wenjie Chen, Mian Ge, Xiaofen Zhong, Linsen Ye, Huaxin Chen, Qi Zhang, Yan Xu   +15 more
wiley   +1 more source