Results 41 to 50 of about 2,326,817 (264)
Function‐driven design of a surrogate interleukin‐2 receptor ligand
FEBS Letters, EarlyView.Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang +9 more
wiley +1 more source
Научный диалог, 2019 The results of research are presented conducted in the framework of the grant RFBR and Volgograd Region Administration (research project 18-49-343006 р_мол_а).
F. A. Taktasheva
doaj +1 more source
Persian Journal of Acarology, 2022 The control of the two spotted spider mite, Tetranychus urticae Koch as one of the most important key pests in agriculture, is basically according to the use of pesticides.
Batool Mokhtari +3 more
doaj +1 more source
Time after time – circadian clocks through the lens of oscillator theory
FEBS Letters, EarlyView.Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo +2 more
wiley +1 more source
THE PROBLEM OF TERRITORIAL ZONING OF THE RUSSIAN FEDERATION: DOMESTIC AND INTERNATIONAL ASPECTS
Vestnik MGIMO-Universiteta, 2018 The current economic regions in Russia were zoned in the 20-30s of the last century by the soviet State Planning Committee. Back then they played an outstanding role in economic development.
V. A. Gorbanyov, B. I. Kochurov
doaj +1 more source
Cell wall target fragment discovery using a low‐cost, minimal fragment library
FEBS Letters, EarlyView.LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan +5 more
wiley +1 more source
Structural biology of ferritin nanocages
FEBS Letters, EarlyView.Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley +1 more source
FEATURES OF NATURAL MOVEMENT OF POPULATION OF NORTH OSSETIA IN POST-SOVIET PERIOD
Наука. Инновации. Технологии, 2022 The article deals with the birth rate, death rate and the natural movement of population of North Ossetia. The article analyzes the characteristics of territorial differentiation of indicators within the republic.
Aleksandr Daurbekovich Badov
doaj
Toxicity and toxicokinetics of the ethanol extract of Zuojin formula
BMC Complementary Medicine and Therapies, 2022 Background Zuojin formula, a traditional Chinese medicine, comprises Coptis chinensis and Evodia rutaecarpa. In our previous study, the total alkaloid extract from Zuojin formula (TAZF) showed potent and improved efficacy.
Shuo Wang +10 more
doaj +1 more source
Childhood exposure to coethnics increases naturalization
Proceedings of the National Academy of SciencesIn Europe, the tendency among immigrants and descendants to seek out and interact with other coethnics has raised concern for their integration as it can reduce contact with the ethnic majority. Though policymakers implement large-scale integration programs to counteract these trends, it remains empirically and theoretically ambiguous ...
openaire +3 more sources