Results 281 to 290 of about 9,504,350 (389)

Surface Elasticity Based Nonlocal Vibration Analysis of Bidirectional Functionally Graded Tapered Nanobeam

Advanced Theory and Simulations, EarlyView.
This work proposes a surface elasticity‐based nonlocal model for analyzing the vibrations of bi‐directionally graded tapered nanobeam. The results demonstrate that, in absence of surface effect, the increasing value of tapered parameter leads to stiffness‐hardening of the nanobeam. However, the consideration of surface effect changes this trend and the
Chinika Dangi, Susmita Naskar
wiley   +1 more source

NeuroLens: organ localization using natural language commands for anatomical recognition in surgical training. [PDF]

Int J Comput Assist Radiol Surg
Matasyoh NM, Delev D, Masalha W, Mathis-Ullrich F, Zeineldin RA.   +4 more
europepmc   +1 more source

Leveraging Transfer Learning to Overcome Data Limitations in Czochralski Crystal Growth

Advanced Theory and Simulations, EarlyView.
A data‐driven framework combining Computational Fluid Dynamics (CFD) simulations and machine learning is proposed to model and optimize Czochralski crystal growth. Using different transfer learning strategies (Warm Start, Merged Training, and Hyperparameter Transfer) the study demonstrates improved predictions for Ge and GaAs growth from Si‐trained ...
Milena Petkovic, Natasha Dropka, Xia Tang, Janina Zittel   +3 more
wiley   +1 more source

Extraction of Social Determinants of Health From Electronic Health Records Using Natural Language Processing. [PDF]

JCO Clin Cancer Inform
Chen Z, Lasserre P, Lin A, Rajapakshe R.
europepmc   +1 more source

CRCFound: A Colorectal Cancer CT Image Foundation Model Based on Self‐Supervised Learning

Advanced Science, EarlyView.
CRCFound is a self‐supervised learning‐based CT image foundation model for colorectal cancer (CRC). Pretrained on 5137 unlabeled CRC CT images, it learns universal feature representations, enabling efficient adaptation to various clinical tasks. The model demonstrates outstanding performance and generalization across multiple diagnostic and prognosis ...
Jing Yang, Du Cai, Junwei Liu, Zhenfeng Zhuang, Yibin Zhao, Feng‐ao Wang, Chenghang Li, Chuling Hu, Baowen Gai, Yiping Chen, Yixue Li, Liansheng Wang, Feng Gao, Xiaojian Wu   +13 more
wiley   +1 more source

Natural Language Processing Improves Reliable Identification of COVID-19 Compared to Diagnostic Codes Alone. [PDF]

Am J Epidemiol
Hendrix N, Parikh RV, Taskier M, Walter G, Phillips RL, Rehkopf DH.   +5 more
europepmc   +1 more source

NOX2 Contributes to High‐Frequency Outer Hair Cell Vulnerability in the Cochlea

Advanced Science, EarlyView.
This study first identifies NOX2 as a differentially expressed gene related to oxidative damage in the apical and basal turns through single‐cell RNA sequencing. NOX2 gene knockout mitigates OHCs damage caused by neomycin and noise and enhances Nrf2 expression and nuclear translocation.
Meihao Qi, Zejun Gao, Yang Qiu, Renfeng Wang, Keyong Tian, Bo Yue, Xinyu Zhang, Peng Zhang, Ziqi Wu, Qingwen Zhu, Zhenzhen Liu, Zhuoyao Ma, Xueying Zhou, Yu Han, Jun Chen, Jianhua Qiu, DingJun Zha   +16 more
wiley   +1 more source

Branched‐Chain α Keto‐Acid Dehydrogenase Kinase‐Mediated AKT Phosphorylation Promotes RCC Tumorigenesis and Drug Resistance

Advanced Science, EarlyView.
This study identifies a novel oncogenic role and a previously unrecognized phosphorylation substrate of BCKDK in RCC, wherein it promotes tumor progression and drug resistance through AKT phosphorylation at both Thr308 and Ser473 sites and activation of AKT/mTOR and AKT/ABCB1 signaling pathways, offering a promising prognostic marker and therapeutic ...
Qin Tian, Jinxiang Wang, Qiji Li, Yangruiyu Liu, Yanping Chen, Jiacheng Feng, Zi‐Ning Lei, Harsh Patel, Chao‐Yun Cai, Yuzhi Xu, Chuntao Quan, Lingyan Fei, Zexiu Xiao, Shuo Fang, Tianxin Lin, Zhe‐Sheng Chen, Yuchen Liu, Leli Zeng, Yihang Pan   +18 more
wiley   +1 more source

A natural language processing approach to support biomedical data harmonization: Leveraging large language models. [PDF]

PLoS One
Li Z, Prabhu SP, Popp ZT, Jain SS, Balakundi V, Alvin Ang TF, Au R, Chen J.   +7 more
europepmc   +1 more source

USP10 Inhibits Ferroptosis via Deubiquinating POLR2A in Head and Neck Squamous Cell Carcinoma

Advanced Science, EarlyView.
This study identifies USP10 as a novel deubiquitinase that antagonizes ferroptosis in head and neck squamous cell carcinoma (HNSCC). Mechanistically, USP10 directly stabilizes POLR2A protein through post‐translational deubiquitination, enabling POLR2A‐mediated transcriptional activation of SLC7A11, a key ferroptosis inhibitor.
Diekuo Zhang, Xueying Wang, Shanhong Lu, Yan Gao, Gangcai Zhu, Guo Li, Zongnan Yu, Junwei Hou, Helei Yan, Wenhui Yuan, Xin Zhang, Mien‐Chie Hung, Zhifeng Liu, Yong Liu   +13 more
wiley   +1 more source