Results 191 to 200 of about 195,991 (305)

Lactylation‐Driven YTHDC1 Alleviates MASLD by Suppressing PTPN22‐Mediated Dephosphorylation of NLRP3

Advanced Science, EarlyView.
In MASLD, YTHDC1 undergoes increased lactylation and ubiquitination, reducing its expression. AARS1 mediates lactylation at lysine 565, while disrupted binding to LDHA further promotes lactylation, suppressing YTHDC1. This downregulation enhances PTPN22 mRNA stability, leading to NLRP3 dephosphorylation and activation, which exacerbates inflammation ...
Feng Zhang, Linghua Zeng, Kunkun Zou, Keying Lin, Fangting Yao, Jinglun Song, Shumeng Zhang, Hanshu Feng, Zhichao Yang, Chunlei Wang, Hongtao Diao, Xue Kong, Tengfei Pan, Joonki Kim, Tianqi Duo, Linqiang Li, Yu Bian   +16 more
wiley   +1 more source

Digital phenotyping of Parkinson's disease via natural language processing. [PDF]

NPJ Parkinsons Dis
Aresta S, Battista P, Palmirotta C, Tagliente S, Lagravinese G, Santacesaria P, Benzini A, Mongelli D, Minafra B, Lunetta C, García AM, Salvatore C.   +11 more
europepmc   +1 more source

Lib2Life – Digital Library Services Empowered with Advanced Natural Language Processing Techniques.

Melania Nițu, Mihai Dascălu, Maria-Dorinela Dascalu, Laurențiu-Marian Neagu, Maria-Iuliana Dascălu   +4 more
openalex   +1 more source

Systematic Evaluation of Research Progress on Natural Language Processing in Medicine Over the Past 20 Years: Bibliometric Study on PubMed (Preprint)

, 2019
Jing Wang, Huan Deng, Bangtao Liu, Anbin Hu, Jun Liang, Lingye Fan, Xu Zheng, Tong Wang, Jianbo Lei   +8 more
openalex   +1 more source

Predicting MammaPrint Recurrence Risk from Breast Cancer Pathological Images Using a Weakly Supervised Transformer

Advanced Science, EarlyView.
This study presents CPMP, a weakly supervised transformer model that predicts MammaPrint recurrence risk directly from routine histopathological images of early‐stage HR+/HER2− breast cancer patients. CPMP enables spatial heatmap visualization, analysis of cellular‐level interaction patterns, and an in‐depth characterization of morphological phenotypes
Chaoyang Yan, Linwei Li, Xiaolong Qian, Yang Ou, Zhidong Huang, Zhihan Ruan, Wenting Xiang, Hong Liu, Jian Liu   +8 more
wiley   +1 more source

Device to Circuit Co‐Design Utilizing High‐Performance PEALD Indium‐Gallium‐Zinc Oxide Thin‐Film Transistor Enabling Technology Node Scaling in Monolithic 3D Systems

Advanced Science, EarlyView.
This article presents a holistic investigation of M3D‐compatible oxide semiconductor technology using PEALD‐fabricated IGZO TFTs, spanning device‐level characterization, TCAD Modeling, circuit design, and scaled‐node projections. It demonstrates high field‐effect mobility (up to 116.35 cm2 V−1·s−1), robust reliability (△VTH < 0.15 V), low variation ...
Wenhui Wang, Tao Zhang, Zelin Yuan, Haoran Peng, Jun Lan, Zhixiong Li, Yongle Wu, Xuewei Feng, Longyang Lin, Feichi Zhou, Panpan Zhang, Yida Li   +11 more
wiley   +1 more source

Development of a natural language-processing application for LGBTQ+ status in mental health records. [PDF]

BJPsych Open
Heslin M, Chaturvedi J, Bonnici Mallia AM, Taaca A, Pontes D, Saraswat C, Woodhead C, Rimes KA, Chandran D, Sanyal J, Ma R, Stewart R, Roberts A.   +12 more
europepmc   +1 more source

Abstract model of a virtual physician assistant for automating medical documentation based on natural language processing and artificial intelligence technologies

Dilara Abzhanova, Sapar Toxanov, Aidos Mukhatayev, Temirlan Karibekov   +3 more
openalex   +1 more source

Subicular Astrocytes Govern Seizure‐Impaired Fear Memory

Advanced Science, EarlyView.
Astrocytes in dorsal subiculum act as a critical modulator of seizure‐associated cognitive dysfunction, operating through a Ca2+‐dependent adenosine‐linked astrocyte‐neuron signaling pathway that disrupts neuronal circuit homeostasis. This research highlights the potential of astrocyte‐targeted interventions as a therapeutic strategy, moving beyond the
Yuying Shao, Jing Xi, Yuhao Sun, Yulan Li, Zhisheng Li, Wangjialu Lu, Jialu Chen, Lin Yang, Fan Fei, Heming Cheng, Li Cheng, Cenglin Xu, Zhuo Huang, Vladimir Parpura, Yi Wang, Zhong Chen   +15 more
wiley   +1 more source

Diagnostic report generation for macular diseases by natural language processing algorithms. [PDF]

Br J Ophthalmol
Zhao X, Li C, Yang J, Gu X, Li B, Wang Y, Zhang BL, Li X, Zhao J, Wang J, Yu W.   +10 more
europepmc   +1 more source