Results 231 to 240 of about 2,544,926 (320)

De Novo Design of Specific Heterotrimeric Collagen‐Like Peptides via Genetic Algorithm

Advanced Science, EarlyView.
GRACE is a computational algorithm producing peptide sequences that will reliably fold into composition and registration‐controlled collagen‐like triple helices with user‐specified thermal stability. Additionally, GRACE allows users to specify the inclusion of biologically relevant (or other) sequences to automatically create tailored triple helices ...
Thi H. Bui, Oluwakamisi Adetunji, Carson C. Cole, Le Tracy Yu, Caroline M. Peterson, Jeffrey D. Hartgerink   +5 more
wiley   +1 more source

Evaluation of falls detected by natural language processing algorithm and not coded external cause of morbidity. [PDF]

JAMIA Open
Hekman DJ, Maru AP, Barton HJ, Wiegmann D, Shah MN, Cochran AL, Ötleş E, Patterson BW.   +7 more
europepmc   +1 more source

PRO‐LDM: A Conditional Latent Diffusion Model for Protein Sequence Design and Functional Optimization

Advanced Science, EarlyView.
PRO‐LDM is a modular latent diffusion framework that learns hierarchical biological representations to enable efficient and high‐fidelity protein design. PRO‐LDM can design species that resemble natural sequences with enhanced diversity or optimize protein functions.
Sitao Zhang, Zixuan Jiang, Rundong Huang, Wenting Huang, Siyuan Peng, Shaoxun Mo, Letao Zhu, Peiheng Li, Ziyi Zhang, Emily Pan, Xi Chen, Yunfei Long, Qi Liang, Jin Tang, Renjing Xu, Rui Qing   +15 more
wiley   +1 more source

A patient-centered approach to developing and validating a natural language processing model for extracting patient-reported symptoms. [PDF]

Sci Rep
Watabe S, Yanagisawa Y, Sayama K, Yokoyama S, Someya M, Taniguchi R, Yada S, Aramaki E, Kizaki H, Tsuchiya M, Imai S, Hori S.   +11 more
europepmc   +1 more source

Drug Resistance Predictions Based on a Directed Flag Transformer

Advanced Science, EarlyView.
 CAPTURE, a deep learning framework combining structural and sequence data to predict drug‐resistant Mpro mutations, revealing that PAXLOVID use may be accelerating resistance—supporting real‐time viral surveillance and therapeutic design. Abstract The evolving SARS‐CoV‐2 virus threatens global public health, particularly with potential resistance to ...
Dong Chen, Gengzhuo Liu, Hongyan Du, Benjamin Jones, Junjie Wee, Rui Wang, Jiahui Chen, Jana Shen, Guo‐Wei Wei   +8 more
wiley   +1 more source

Sensitivity and Specificity of Natural Language Processing Systems for Identification of Hospitalized People Who Use Drugs. [PDF]

Open Forum Infect Dis
Benrubi L, Sato T, Westgard LK, Zollo-Venecek K, Socrates B, Sweigart B, Ridgway JP, Suzuki J, Morales Y, Goodman-Meza D, Wurcel AG.   +10 more
europepmc   +1 more source

Parvalbumin Interneuron‐Dependent Hippocampal Neurogenesis Evoked by Prolonged Rhythmic Light Flicker

Advanced Science, EarlyView.
This study demonstrates that prolonged rhythmic 40 Hz light flicker enhances spatial learning by stimulating PV interneuron‐dependent neurogenesis. The light flicker selectively activates PV interneurons, which enhances GABAergic support for the integration of immature neurons in the adult dentate gyrus.
Hai Yan, Yunxuan Wang, Xufan Deng, Shiyu Wu, Yifan Pan, Jun Du, Mei Yu, Bo Liu, Huimei Wang, Zhengyu Zhang, Jinghong Chen, Shuifa Chen, Yizheng Wang, Tara Walker, Perry Bartlett, Jun Ju, Sheng‐Tao Hou   +16 more
wiley   +1 more source

Unveiling Arabic named entity recognition using natural language processing with artificial intelligence approach on Moroccan dialect. [PDF]

Sci Rep
Subait WB, Ahmad N, Alzaidi MSA, Alqahtani M, Alhashmi AA, Aljehane NO, Alshahrani M, Alotaibi SD.   +7 more
europepmc   +1 more source

Natural Language Processing and XML Retrieval. [PDF]

, 2006
Alan Woodley, Shlomo Geva, Marcus Hassler, Xavier Tannier   +3 more
openalex  

A Myelin Debris Cleaner for Spinal Cord Injury Recovery: Polycaprolactone / Cell Membrane Assembled Scaffolds

Advanced Science, EarlyView.
pMM‐PCL, made up of pretreated macrophage menbrane and polycaprolactone, boasts the adsorption of harmful myelin debris in the microenvironment of spinal cord injury. Abstract After spinal cord injury (SCI), a mass of myelin debris derived from injured myelin sheath will be consistently generated and induce macrophages to be foam cells.
Yuchen Zhou, Tao Xu, Yiyan Zhou, Nuo Chen, Zhengchao Wu, Zongze Yang, Changwei Yang, Xiaoqing Chen   +7 more
wiley   +1 more source