Results 41 to 50 of about 74,001 (261)
Notre Dame Journal of Formal Logic, 1991 zbMATH Open Web Interface contents unavailable due to conflicting licenses.
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Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer
Molecular Oncology, EarlyView.Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola +11 more
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FEBS Open Bio, EarlyView.Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero +5 more
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Directed evolution of enzymes at the crossroads of tradition and innovation
FEBS Open Bio, EarlyView.An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova +2 more
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, 1984 The argument in this paper is that there exist a very large number of well-formed sentences which do not seem natural to a sensitive native speaker; therefore these sentences must violate some restrictions which are not among the criteria for well-formedness. It is important to examine what the further restrictions might be, for at least three reasons:
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FEBS Open Bio, EarlyView.Miniaturized flow chip platform enabling continuous perfusion and longitudinal multiphoton 3D imaging of vascular smooth muscle cell constructs under physiological flow. Brightfield imaging guides region selection, while CellTracker Green and mRuby‐labeled fetuin‐A visualize cells and mineral deposition, respectively. Magnesium supplementation markedly
Vytautas Kučikas +6 more
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RAGLRO: Retrieval‐Augmented Generation With Large Language Models for Robotic Operations
CAAI Transactions on Intelligence TechnologyTo enable autonomous operations in complex industrial environments, this paper proposes retrieval‐augmented generation with large language models for robotic operations (RAGLRO), a robotic framework specifically designed for power switchgear operation ...
Wenrui Wang +6 more
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Proceedings of the workshop on Speech and Natural Language - HLT '89, 1989 Except for the final presentation by Hovy, this session focussed on the use of superficial features of Natural Language in text processing (messages, in the case of the first two presentations, unrestricted text in the case of the second two). This is a very brief summary of a moderator's view of the action.
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Evolution‐guided yeast complementation reveals functional differences in human PSPH variants
FEBS Open Bio, EarlyView.Ancient genomes can help guide which human genetic variants are tested experimentally. This study applies that idea to PSPH, a gene involved in serine biosynthesis, and uses high‐throughput yeast complementation to compare variant function. The findings reveal measurable differences among selected alleles and illustrate the value of evolution‐guided ...
Mauricio Campa‐Álvarez +6 more
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What are Languages? A Biolinguistic Perspective
Open Linguistics, 2014 The goal of the present contribution is to explore what kinds of objects languages are from a biolinguistic point of view. I define the biolinguistic point of view as a naturalistic study of languages and I show that from this point of view, languages ...
Mendívil-Giró José-Luis
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