Results 81 to 90 of about 75,668 (308)

Avaliação de ferramentas de simulação de iluminação natural por meio de mapeamento digital de luminâncias da abóboda celeste e entorno [PDF]

open access: yes, 2009
Tese (doutorado) - Universidade Federal de Santa Catarina, Centro Tecnológico. Programa de Pós-graduação em Engenharia CivilEntre os métodos de maior potencial para a análise do fenômeno da iluminação natural no ambiente construído, encontram-se a ...
Pereira, Roberto Carlos
core  

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

open access: yesFEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane   +11 more
wiley   +1 more source

Natural Lighting in Historic Houses during Times of Pandemic. The Case of Housing in the Mediterranean Climate. [PDF]

open access: yesInt J Environ Res Public Health, 2021
Muñoz-González C   +6 more
europepmc   +1 more source

Iluminação natural em edificações : calculo de iluminancias internas-desenvolvimento de ferramenta simplificada [PDF]

open access: yes, 1997
Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro TecnologicoO trabalho tem como escopo a definição de uma metodologia para determinação de iluminâncias em plano horizontal no ambiente construído sob condições de céu encoberto e céu
Souza, Roberta Vieira Gonçalves de
core  

Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling

open access: yesFEBS Open Bio, EarlyView.
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero   +5 more
wiley   +1 more source

Designing Atmospheres: A Natural and Lively Luminous Environment Through Dynamic Lighting

open access: yes, 2021
Throughout history, the main goal of office lighting has been to increase efficiency through bright lighting having an even distribution. Yet, recent research indicates that this kind of lighting leads to an unstimulating, boring, and dull luminous ...
Sigura, Verda
core  

Early‐life high‐fat diet exposure increases Achilles tendon stiffness and induces transcriptomic alterations

open access: yesFEBS Open Bio, EarlyView.
Early‐life exposure to a high‐fat diet altered intact Achilles tendons in rat offspring, making them thinner, stiffer, and molecularly distinct even without injury. These findings suggest that developmental high‐fat diet exposure may impair tendon quality and increase susceptibility to mechanical overload or tendon injury later in life.
Heyong Yin   +3 more
wiley   +1 more source

Research on Road Lighting Control Strategies Based on the Impact of Different Lighting Sources on Driver Visibility

open access: yesApplied Sciences
This study analyzes the characteristics of natural lighting and artificial lighting illuminance, correlated color temperature (CCT), and color rendering index (CRI), and their impact on driver visibility. A real-vehicle experiment was conducted to assess
Zechao Zhang   +3 more
doaj   +1 more source

A influência de elementos de obstrução solar no nível e na distribuição interna de iluminação natural: estudo de caso em protótipo escolar de Florianópolis [PDF]

open access: yes, 2002
Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro Tecnológico. Programa de Pós-Graduação em Engenharia Civil.O correto aproveitamento da iluminação natural é inseparável do bom projeto de arquitetura, entretanto a maior parte dos ...
Kremer, Adriano
core  

Versatile vector tools for efficient protein screening across multiple expression systems

open access: yesFEBS Open Bio, EarlyView.
A unified vector toolkit enables rapid protein expression screening across E. coli, insect, and mammalian cells. A single primer pair amplifies the target gene, which is inserted into any vector via a standardized interface. This streamlined workflow eliminates repeated cloning steps, accelerating the identification of optimal expression conditions for
Zhimin Zhu   +5 more
wiley   +1 more source

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