Results 51 to 60 of about 391,233 (284)

Phosphoinositides and inositol phosphates as molecular glues

FEBS Letters, EarlyView.
Inositol phosphates (IPs) and phosphoinositides (PIPs) regulate diverse eukaryotic processes. Beyond recruiting signaling proteins or acting as structural cofactors, recent studies suggest they mediate protein–protein interactions as natural molecular glues.
Aleshia Seaton‐Terry, Alexander J. Cutright, Mong Na Claire Loi, Jessica Martin, Joseph W. Gilligan, Jakub N. Kubina, Michael J. Arambula, Susanna Tanada Palmu, Daniella Zhou, Raymond D. Blind   +9 more
wiley   +1 more source

An Analytical Technique, Based on Natural Transform to Solve Fractional-Order Parabolic Equations

Entropy, 2021
This research article is dedicated to solving fractional-order parabolic equations using an innovative analytical technique. The Adomian decomposition method is well supported by natural transform to establish closed form solutions for targeted problems.
Ravi P. Agarwal, Fatemah Mofarreh, Rasool Shah, Waewta Luangboon, Kamsing Nonlaopon   +4 more
doaj   +1 more source

Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates

FEBS Letters, EarlyView.
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley   +1 more source

The Fujiki class and positive degree maps

Complex Manifolds, 2015
We show that a map between complex-analytic manifolds, at least one ofwhich is in the Fujiki class, is a biholomorphism under a natural condition on the second cohomologies.
Bharali Gautam, Biswas Indranil, Mj Mahan   +2 more
doaj   +1 more source

Hydrate Dissociation Model with Time Fractional Derivative

Geofluids, 2022
In this paper, we shall investigate fractional partial differential equations with fractional moving boundary condition to study the dissociation of natural gas hydrate under heat injection.
Xinyu Fang, Hairong Lian, Wanjing Luo, Mingzhu Liu, Changfu Chen, Qian Wang   +5 more
doaj   +1 more source

Logic program specialisation through partial deduction: Control Issues

, 2002
Program specialisation aims at improving the overall performance of programs by performing source to source transformations. A common approach within functional and logic programming, known respectively as partial evaluation and partial deduction, is to ...
Bruynooghe, Maurice, Leuschel, Michael
core   +1 more source

Reconstructing enzyme evolution by protein engineering

FEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler, Markus R. Busch, Reinhard Sterner   +2 more
wiley   +1 more source

Employing the Double Natural Generalized Laplace Transform to Solve Singular Boussinesq Equations in Two Dimensions

Fractal and Fractional
The double natural generalized Laplace transform decomposition method (DNGLTDM) is proposed as a new approach for solving singular linear and non-linear two-dimensional Boussinesq equations involving fractional partial derivatives.
Hassan Eltayeb, Shayea Aldossari
doaj   +1 more source

Ultrasonic Detection Sensor of Digital Distribution Network Based on EFPI

Zhongguo dianli, 2023
In order to meet the demand of partial discharge ultrasonic signal detection of digital distribution network equipment, an ultrasonic sensor based on extrinsic Fabry Perot interferometric (EFPI) is developed to detect the ultrasonic signal generated by ...
Ling JU, Yi HUANG
doaj   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source