Results 141 to 150 of about 242,335 (291)
Stroke‐induced lactate accumulation promotes p300‐mediated lactylation of methyl‐CpG binding protein 2 (MeCP2) at lysine 210, which reprograms microglial metabolism toward glycolysis and activates the hexokinase 2 (HK2)/mTOR axis. This cascade promotes proinflammatory responses and impairs neurofunctional outcomes.
Zengyu Zhang +12 more
wiley +1 more source
AGGREGATE STABILITY OF AN ULTISOL IN REGIONS OF THE BRAZILIAN AMAZON
The aggregate stability is essential for water infiltration, soil aeration and root penetration resistance, impacting water infiltration, moisture retention, soil aeration and root penetration resistance. Inadequate agricultural practices can limit root
Diego Lima de Souza Cruz +5 more
doaj +1 more source
Participatory design and use of a simplified landscape in a simulation model for mitigating land use conflict in Northern Thailand highlands [PDF]
Landscape modelling integrating spatial information in Geographic Information Systems has been widely used to represent knowledge and support decision-making in the field of natural resource management.
Dumrongrojwatthana, P. +3 more
core
This study reveals that XBP1s drives production of circTspan3, a circular RNA that strengthens cartilage by boosting anabolic activity and limiting cell death. Phosphorylated ANXA2 directs circTspan3 into exosomes, enabling paracrine repair. Exosomal circTspan3 expands growth‐plate cartilage and promotes in vivo regeneration, highlighting its promise ...
Yiming Pan +16 more
wiley +1 more source
Interactions between trees, crops and animals: experiences in a novel bioenergy-livestock system in the UK [PDF]
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Smith, J.
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T cell‐specific Socs1 knockout leads to inflammatory differentiation of CD8+ T cells, prompting the STAT1/2 complex to drive the activation of Ccl5, Ccr5, and Cxcr3, and promoting the skewing of monocytes toward a pro‐inflammatory M1 macrophage lineage.
Zhigui Wu +14 more
wiley +1 more source
Creating a Northern Agriculture. III. Defining Parameters of Agricultural Potential in Alaska [PDF]
Alaska's current land-use planning is characterized by a particular void in providing for future agricultural development. One reason for this void in planning has been a profound lack in identification of production possibilities in most areas of the
Burton, Wayne E.
core
Nap1l4a is required in erythropoiesis and hypoxia responses via physical interaction with Klf1 and Scl to recruit the histone variant H2A.Z. This facilitates its associated cis‐regulatory element (CRE) remodeling and the consequent chromatin assembly, and activates the transcription of erythroid lineage‐specific genes.
JiaHao Shi +10 more
wiley +1 more source
Este trabalho foi realizado com o objetivo de verificar a resposta de uma pastagem natural na Depressão Central do Rio Grande do Sul à adubação com chorume suíno nas doses de 0, 15, 30 e 45 m³/ha, equivalentes a 76,8; 153,7 e 230,5 kg N/ha/corte depois de cada um dos quatro cortes, realizados no período de outubro de 2003 e fevereiro de 2004 ...
Simone Meredith Scheffer-Basso +2 more
openaire +1 more source
Hungry for Knowledge: Octopamine Signaling Regulates Hunger‐Enhanced Olfactory Learning
Researchers demonstrate that hunger state facilitates both aversive and appetitive olfactory learning. Two distinct octopamine signaling pathways are involved in aversive or appetitive memory formation in the hunger state. And, hunger state also facilitates the formation of both types of memories via an evolutionarily conserved norepinephrine (the ...
Huijuan Zhao +14 more
wiley +1 more source

