Results 71 to 80 of about 2,218 (218)
Aquaporin‐3 and aquaporin‐5 impact the development of pancreatic ductal adenocarcinoma spheroids
FEBS Open Bio, EarlyView.Schematic representation of the role of aquaporin‐3 (AQP3) and aquaporin‐5 (AQP5) in pancreatic ductal adenocarcinoma (PDAC). Both proteins are upregulated in PDAC and are associated with tumor progression and metastatic potential. Silencing AQP3 or AQP5 in PDAC spheroids results in decreased diameter, area, and overall growth, underscoring their key ...
Catarina Pimpão +3 more
wiley +1 more source
Directed evolution of enzymes at the crossroads of tradition and innovation
FEBS Open Bio, EarlyView.An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova +2 more
wiley +1 more source
STATUS OF ENTREPRENEUR – NATURAL PERSON [PDF]
Challenges of the Knowledge Society, 2011 The necessity of limitation of the entrepreneur as a natural person who organizes an economic company within which the economic activity is developed in an organized, permanent and systematic way, combining the financial resources, the attracted labor ...
SILVIA CRISTEA, ANGELICA ROSU
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MagmaFlow: A desktop platform for artificial intelligence‐driven expression analysis
FEBS Open Bio, EarlyView.MagmaFlow is a free, no‐code platform for gene expression analysis. It generates interactive volcano plots, links genes to literature, pathways, and diseases, prioritizes candidates using millions of publications, identifies affected biological processes, builds network diagrams, and exports publication‐ready figures and reports for macOS and Windows ...
Carlos E. Buss +7 more
wiley +1 more source
Importin 7 mediates the nuclear import of HIV‐1 integrase via a specific interacting interface
FEBS Open Bio, EarlyView.HIV‐1 integrase enables viral DNA integration into the host genome. By binding to the core domain of the host protein Importin 7 via its C‐terminal domain, the integrase is transported across the nuclear membrane into the nucleus, where integration of the viral genome into host DNA takes place. This translocation is a critical step for subsequent viral
Juana Bana +5 more
wiley +1 more source
Criminal and administrative liability of legal persons in the Czech Republic [PDF]
Košická bezpečnostná revue, 2019 The issue of liability of legal persons for criminal acts and for offenses is relatively new. The liability of legal persons for criminal acts is based on the so-called imputability of the fault of the natural person who acted for the legal person ...
Roman SVATOŠ
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Malformin A1–mediated cytotoxicity in ovarian cancer cells occurs through pyroptosis and autophagy
FEBS Open Bio, EarlyView.This study investigated the effects of the natural compound Malformin A1 (MA1) on the cytoskeleton that regulates cell proliferation and migration. Disruption of the cytoskeleton can impair these processes and promote cancer cell death. MA1 disrupted cytoskeletal organization, induced DNA damage, inflammation, activated autophagy, and pyroptosis ...
Nada Abdullah Hassan +11 more
wiley +1 more source
A person with intellectual disability as a client of an employment office. Natural assistantship [PDF]
Edukacja Ustawiczna Dorosłych, 2019 The article presents the model of natural assistantship as means to adapt the offer of public employment services to the needs of people with intellectual disabilities because benefiting from the support of public sector is a basic citizen’s ...
Mariola WOLAN-NOWAKOWSKA
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Evaluating the effect of γ‐oryzanol on MASLD pathology using a medaka fish model
FEBS Open Bio, EarlyView.This study explores a liver disease called MASLD, which is increasing worldwide and can lead to serious damage. Researchers used medaka fish instead of rodents to test a food compound, γ‐oryzanol. Fish fed this compound had less liver fat and healthier gut bacteria.
Yukako Ito +7 more
wiley +1 more source
ECONOMIC AND SOCIAL DIMENSIONS OF AGRI-FOOD SECTOR IN THE SLOVAK REPUBLIC [PDF]
Scientific Papers Series : Management, Economic Engineering in Agriculture and Rural DevelopmentThe aim of the paper is to analyse selected economic and social aspects of the agri-food sector in the Slovak Republic. The source of data was the Statistical Office of the Slovak Republic as well as the National Agricultural and Food Centre Branch ...
Maroš VALACH
doaj