Results 81 to 90 of about 5,242,006 (252)

Characterization of therapeutic antibodies targeting lymphatic and vascular resistance factor for the treatment of hypervascularized and highly metastatic cancers

Molecular Oncology, EarlyView.
LVRF (lymphatic and vascular resistance factor) is a VEGFA splice variant upregulated in response to anti‐angiogenic therapy that fosters tumor adaptation through enhanced vascularization, lymphangiogenesis, and metastatic dissemination. Targeting LVRF with fully human neutralizing antibodies disrupts these processes and limits resistant tumor growth ...
Marion David, Arthur Karaulic, Audrey Bennetot, Clémence Fournier, Quentin Odet, Arthur Gouraud, Isabelle Bourget, Cédric Gaggioli, Sandy Giuliano, Frédéric Luciano, Olivier Léger, Zaki Sellam, Gilles Pagès   +12 more
wiley   +1 more source

Măsurile contractuale și judiciare de ocrotire a persoanei fizice adulte: noțiuni introductive

Revista Institutului Naţional de Justiţie, 2018
Defining aspects on the contractual and judicial protection measures of adult natural persons The legal capacity of natural persons has a different regulation into national law, so that natural persons cannot be claimed incapable.
Cazacu Doina
doaj  

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

FEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli, Mohammad Nour Alsamsam, Ugnė Bagdonaitė, Van Truc Vu, Chun‐Jen Huang, Polina Kuzhir, Mindaugas Zaremba, Aurimas Kopūstas, Marijonas Tutkus   +8 more
wiley   +1 more source

Aquaporin‐3 and aquaporin‐5 impact the development of pancreatic ductal adenocarcinoma spheroids

FEBS Open Bio, EarlyView.
Schematic representation of the role of aquaporin‐3 (AQP3) and aquaporin‐5 (AQP5) in pancreatic ductal adenocarcinoma (PDAC). Both proteins are upregulated in PDAC and are associated with tumor progression and metastatic potential. Silencing AQP3 or AQP5 in PDAC spheroids results in decreased diameter, area, and overall growth, underscoring their key ...
Catarina Pimpão, Diogo M. Engrácia, Graça Soveral, Filipa Mendes   +3 more
wiley   +1 more source

A study of the nature and determinants of non-disabled persons attitudes towards persons with physical disabilities and disabled persons attitudes towards their disabilities and self-acceptance as measured by the attitudes toward disabled persons scale [PDF]

, 1975
Includes bibliographical references.The research objectives of this study were to test a number of hypothesized relationships between the dependent variables, that is, attitudes towards disabled persons and attitude intensity, and certain independent ...
Riese, Edward David
core   +1 more source

The Guardianship Mandate

Erdélyi Jogélet
The Constitutional Court of Romania, in its Decision No 601 of 16 July 2020, declared Article 164 (1) of the Romanian Civil Code on the placement of persons under judicial guardianship as unconstitutional.
Előd Bartis
doaj   +1 more source

Minutes from Displaced Persons Committee meeting - October 28, 1949

, 1949
This report of minutes from the October 28, 1949, Displaced Persons Committee meeting in Newark, records the Committee's plans for lobbying the New Jersey state government to create a State Commission on Displaced Persons.
Displaced Persons Committee
core   +1 more source

Directed evolution of enzymes at the crossroads of tradition and innovation

FEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova, Andrej Mirossay, Erik Sedlak   +2 more
wiley   +1 more source

Final report /

, 2007
Title from cover.; "Report Prepared by the Permanent Commission on the Status of Women."; "January 2007."; Mandated by Public Act no. 06-43, an Act Concerning Trafficking in Persons.; Includes bibliographical references.; Harvested from the web on 12/14 ...
Connecticut. General Assembly. Interagency Task Force on Trafficking in Persons.
core   +1 more source

Minutes from a Displaced Persons Committee meeting - May 13, 1949

, 1949
These minutes from the May 13, 1949, meeting of the Displaced Persons Committee, review the Committee's plans for assisting the New Jersey Governor's office with the establishment of the New Jersey State Commission on Displaced Persons.
Displaced Persons Committee
core   +1 more source