Results 41 to 50 of about 4,647,046 (244)

Targeting LDHA Palmitoylation Sensitizes GBM to Chemoradiotherapy via Suppressing Palmitic Acid Induced Glycolytic Reprogramming

Advanced Science, EarlyView.
Mesenchymal GSCs preferentially uptake palmitic acid, thereby promoting ZDHHC12‐mediated LDHA palmitoylation. This modification enhances LDHA enzymatic activity, drives glycolytic reprogramming, and facilitates exosomal LDHA‐mediated TAM regulation.
Zijie Gao, Rongrong Zhao, Zheyuan Chen, Qingtong Wang, Huanyu Yang, Boyan Li, Yanhua Qi, Shulin Zhao, Jixing Zhao, Jiawei Qiu, Ziwen Pan, Zhe Han, Ruochuan Li, Huize Xia, Weijie Tang, Xing Guo, Ping Zhang, Hongyu Zhao, Xu Qian, Gang Li, Hao Xue   +20 more
wiley   +1 more source

Radioactivity and radionuclides in deciduous teeth formed before the Fukushima-Daiichi Nuclear Power Plant accident

Scientific Reports, 2021
The Fukushima-Daiichi Nuclear Power Plant (FNPP) accident in March of 2011 released substantial amounts of radionuclides into the environment. We collected 4,957 deciduous teeth formed in children before the Fukushima accident to obtain precise control ...
Atsushi Takahashi, Mirei Chiba, Akira Tanahara, Jun Aida, Yoshinaka Shimizu, Toshihiko Suzuki, Shinobu Murakami, Kazuma Koarai, Takumi Ono, Toshitaka Oka, Joji Ikeyama, Osamu Kaneko, Makoto Unno, Kimiharu Hirose, Takashi Ohno, Yasushi Kino, Tsutomu Sekine, Ken Osaka, Keiichi Sasaki, Hisashi Shinoda   +19 more
doaj   +1 more source

Radiation‐Triggered Chemokine‐Secreting Probiotics for Boron Neutron Capture Therapy Based Radioimmunotherapy

Advanced Science, EarlyView.
Engineered Escherichia coli Nissle 1917 with a tannic acid‐mediated BPA coating enables tumor‐targeted boron delivery for BNCT. The low‐level incidental radiation generated during BNCT activate a RecA‐driven circuit to induce CXCL10, while radiation‐enhanced bacterial colonization triggers in situ vaccination and systemic antitumor immunity.
Yang Liu, Yuzhong Qian, Shaobo Huang, Bingbing Li, Yue Yu, Xiang Cheng, Chang Chen, Jiheng Wang, Maosong Yang, Lizheng Liang, Xiancai Meng, Zhigang Liu   +11 more
wiley   +1 more source

Survey of Natural and Anthropogenic Radioactivity in Environmental Samples from Yugoslavia

, 2002
The radioactivity of 238U, 226Ra, 232Th, 40K and 137Cs in sediments, soil, turf and honey from Serbia and Kosovo (Yugoslavia) was measured using gamma and alpha spectrometry in order to estimate the radiation hazard from natural and man-made sources, as ...
Esposito, M., Bartolomei, P.
core   +3 more sources

Radiological Risk to Human and Non-Human Biota Due to Radioactivity in Coastal Sand and Marine Sediments, Gulf of Oman

Life, 2021
Natural and 137Cs radioactivity in coastal marine sediment samples was measured using gamma spectrometry. Samples were collected at 16 locations from four beaches along the coastal area of Muscat City, Gulf of Oman.
Ibrahim I. Suliman, Khalid Alsafi
doaj   +1 more source

Near‐Infrared Fluorescent PROTAC Enables Theranostic Imaging and Selective Tau Degradation in Alzheimer's Disease

Advanced Science, EarlyView.
Here, we report a novel NIR fluorescent PROTAC platform that enables real‐time imaging and targeted degradation of Alzheimer's p‐Tau. Our lead compound effectively clears p‐Tau, reduces APP/Aβ, and alleviates cognitive deficits in AD mice. This work demonstrates a theranostic strategy for visualizing degradation and developing next‐generation AD ...
Ziwei Ren, Qian Yue, Ning Gao, Qiu‐Lian Hao, Yan Huo, Chuchu Li, Xinyue Leng, Lu‐Lu Sun, Maggie Pui Man Hoi, Hai‐Hao Han, Mingliang Ma, Xu‐Wen Li   +11 more
wiley   +1 more source

Natural radioactivity measurements in soil samples of Central Kutahya (Turkey)

, 2008
Measurement of the natural radioactivity of surface soils at 20 locations in central Kutahya has been made using gamma ray spectroscopy. Natural gamma ray radioactivity of the terrestrial nuclides in soil samples and the absorbed gamma ray dose rates of ...
Cavas, Mustafa, Sahin, Latife
core   +1 more source

Calibration with MCNP of NaI detector for the determination of natural radioactivity levels in the field [PDF]

, 2016
In view of assessing natural radioactivity with on-site quantitative gamma spectrometry, efficiency calibration of NaI(Tl) detectors is investigated.
Cinelli, Giorgia, TOSITTI, LAURA, MOSTACCI, DOMIZIANO, Baré, Jonathan   +3 more
core   +1 more source

Dual‐Target Nectin‐4/FAP Heterobivalent Probe 68Ga/177Lu‐FZ‐NF‐1 for Triple‐Negative Breast Cancer: Preclinical Theranostic Evaluation and First‐in‐Human Translation

Advanced Science, EarlyView.
A novel hetero‐bivalent agent, 68Ga/177Lu‐FZ‐NF‐1, concurrently targets Nectin‐4 and FAP in triple‐negative breast cancer. It yields significant preclinical tumor regression and clinically identifies additional metastatic lesions missed by 18F‐FDG PET, demonstrating promising theranostic potential for personalized management.
Ye Li, Li Sun, Xiaoyu Pan, Shuyi Lin, Dongliang Wang, Jianping Zhang, Fengshuang Qiu, Bin Zhu, Lingzhou Zhao, Fengsheng Zhang, Liyan Bai, Bingxin Gu, Xiaoping Xu, Shaoli Song   +13 more
wiley   +1 more source

Utilization of phosphogypsum and red mud in alfalfa cultivation

Heliyon
In this work, the utilization of phosphogypsum (PG), a waste coming from the manufacture of phosphate fertilizers, as fertilizer for alfalfa (Medicago sativa L.) crops was investigated using pot experiments.
Pedro Palencia, José Luis Guerrero, Rebeca Millán, Fernando Mosqueda, Juan Pedro Bolívar   +4 more
doaj   +1 more source