T Cell Exhaustion in Cancer Immunotherapy: Heterogeneity, Mechanisms, and Therapeutic Opportunities
T cell exhaustion limits immunotherapy efficacy. This article delineates its progression from stemālike to terminally exhausted states, governed by persistent antigen, transcription factors, epigenetics, and metabolism. It maps the exhaustion landscape in the TME and proposes integrated reversal strategies, providing a translational roadmap to overcome
Yang Yu +7 more
wiley +1 more source
Mechanical behavior of reservoir bank slope-pile-sheet structures under reservoir operation: Field monitoring and numerical simulation analysis. [PDF]
Cai Z +7 more
europepmc +1 more source
Integrated reservoir quality index (IRQI): a novel approach for reservoir quality assessment. [PDF]
Leisi A, Kadkhodaie A, Kadkhodaie R.
europepmc +1 more source
A bacterial gene acquired by parasitoid wasps contributes to venom secretion against host defence. [PDF]
Liu Z +16 more
europepmc +1 more source
Spontaneous chlorine production from chloride-containing brines. [PDF]
Zhu C +6 more
europepmc +1 more source
Characteristics of Reservoir Boundary Ranging with While-Drilling Impulse Sound Source. [PDF]
Shang H, Gao S.
europepmc +1 more source
Environmental degradation as a recipe for emerging viral diseases: implications for global health. [PDF]
Hudu SA +3 more
europepmc +1 more source
Natural reservoirs of Trypanosoma cruzi.
openaire +1 more source

