Results 31 to 40 of about 4,781,742 (304)

From junk to function — How weak selection in eukaryotes builds new parts and drives genomic complexity

open access: yesFEBS Letters, EarlyView.
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley   +1 more source

Sedimentation-capacity model of the subsalt deposits of the Southern Urals and adjoining territories

open access: yesGeoresursy, 2019
The junction zone of the Caspian syneclise, the Russian Plate and the Pre-Ural trough is characterized by a complex structure. It has been studied in some detail during large-scale geological, geophysical, and drilling operations in the search for ...
V.A. Zhemchugova   +4 more
doaj   +1 more source

A reservoir simulation approach for modeling of naturally fractured reservoirs

open access: yesEgyptian Journal of Petroleum, 2012
AbstractIn this investigation, the Warren and Root model proposed for the simulation of naturally fractured reservoir was improved. A reservoir simulation approach was used to develop a 2D model of a synthetic oil reservoir. Main rock properties of each gridblock were defined for two different types of gridblocks called matrix and fracture gridblocks ...
H. Mohammadi   +2 more
openaire   +2 more sources

On the response of a reservoir sidearm to diurnal heating and cooling [PDF]

open access: yes, 1993
During the day, the shallower regions of a reservoir sidearm absorb more heat per unit volume than the deeper parts, leading to a horizontal pressure gradient that drives a circulation in the sidearm.
Farrow, D.E., Patterson, J.C.
core  

Reservoir computing with output feedback [PDF]

open access: yes, 2011
Reinhart RF. Reservoir computing with output feedback. Bielefeld: Bielefeld University; 2011.A dynamical system approach to forward and inverse modeling is proposed. Forward and inverse models are trained in associative recurrent neural networks that are
Reinhart, René Felix, Reinhart, Felix
core   +1 more source

The heterodimeric amino acid transporters (HAT) of the SLC7/SLC3 family: A structure−function relationships and relevance to human pathology

open access: yesFEBS Letters, EarlyView.
Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise   +5 more
wiley   +1 more source

Carbonate reservoirs of subsalt deposits of the Caspian syneclise

open access: yesGeoresursy, 2017
The Caspian syneclise is one of the most promising hydrocarbon regions in Russia and Kazakhstan, which is confirmed by the discovery in recent years of large oil and gas fields within its borders.
V.A. Zhemchugova   +4 more
doaj   +1 more source

Marine reservoir corrections for Moreton Bay, Australia [PDF]

open access: yes, 2009
We present the first direct assessment of marine reservoir effects in the Moreton Bay region using radiocarbon dating of known-age, pre-AD 1950, shell samples from the east coast of Stradbroke Island and archaeological shell/charcoal pairs from Peel ...
Petchey, F.   +6 more
core   +1 more source

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

open access: yesMolecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary   +1 more
wiley   +1 more source

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

open access: yesFEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli   +8 more
wiley   +1 more source

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