Results 41 to 50 of about 1,666 (264)

Targeting Dnmt3a/m5C/RelA Axis Attenuates Microglia Inflammatory Response and Improves Postoperative Recovery in Chronic Compressive Cervical Spinal Cord Injury

Advanced Science, EarlyView.
A pro‐inflammatory microglial subset persists after decompression in chronic compressive cervical spinal cord injury and shows enhanced Dnmt3a‐driven m5C signaling. By stabilizing RelA mRNA, this axis sustains NF‐κB activation and postoperative neuroinflammation.
Tianyu Qin, Yuan Jiang, Yongheng Xie, Huanwei Qu, Wenbin Yan, Jingle Chen, Yining Chen, Huayi Li, Naibo Feng, Jiajun Wu, Chao Zhang, Zhengqi Huang, Ming Shi, Zhihuai Deng, Guozhi Xiao, Houqing Long   +15 more
wiley   +1 more source

Leveraging financial development, trade openness, urbanization, governance, and natural resources to alleviate energy poverty

Discover Global Society
Energy poverty is being faced by various countries in the world, and the African states are not an exception. This research examines the role of natural resource rents, financial development, governance, trade openness, and urbanization in shaping energy
Abraham Deka, Aliya Zhakanova
doaj   +1 more source

Are Natural Resources a Curse for Green Growth in OECD Countries? The Moderating Role of Green Innovations and Environmental Regulations

Risks
This study empirically examines the impact of natural resource rents (NRR), a proxy for economic benefits and costs of natural resources, on green growth (GG) in Organization for Economic Co-operation and Development (OECD) countries from 1996 to 2020 ...
Shomaila Habib, Huan Qiu, Anum Rashid, Yiwei Zhao, Jimmy Chien   +4 more
doaj   +1 more source

Spillovers effect of gas price on macroeconomic indicators: A GVAR approach

Energy Reports, 2023
The demand for natural gas as a transitional fuel has been increasing steadily due to global energy transitions. However, the high concentration of natural gas sources among a few producers and the dependence of many consuming economies raises questions ...
Seyed Reza Mirnezami, Kazi Sohag, Mohammad Jamour, Fazel Moridi-Farimani, Ahmad Hosseinian   +4 more
doaj   +1 more source

ZNF33B Promotes Japanese Encephalitis Virus Infection by Regulating the Stability of M6A‐Modified Trim25 to Control the Autophagy Process

Advanced Science, EarlyView.
Upon JEV infection, ZNF33B recruits METTL14 to stabilize the METTL3‐METTL14 m6A methyltransferase complex, leading to increased m6A modification of host transcripts, including Trim25 mRNA. ZNF33B selectively binds m6A‐modified sites on Trim25 mRNA and accelerates its decay, resulting in reduced TRIM25 protein abundance.
Jian Du, Chunwei Li, Jiyuan Luo, Huizhi Zhang, Jinyan Zhang, Suya Wang, Huanchun Chen, Hongli Xu, Xiangmin Li, Ping Qian   +9 more
wiley   +1 more source

Radiation‐Induced Tumor‐Intrinsic LTβR N‐Glycosylation Suppresses Pyroptosis Through TRIM28‐Mediated PCBP2 SUMOylation to Promote Gastric Cancer Radioresistance

Advanced Science, EarlyView.
Radiotherapy triggers LTβR N‐glycosylation, enhancing its overall protein stability and nuclear retention. This accumulation drives TRIM28‐mediated PCBP2 SUMOylation, suppressing pyroptosis and conferring gastric cancer radioresistance. Therapeutically, a targeted nanoplatform (cRGD‐Lipo@EMD) effectively disrupts this regulatory axis, offering a highly
Weijie Zang, Yunlong Ji, Chunwang Zhou, Xiwen Li, Zhuang Lu, Guangze Zhang, Yu Chen, Wanjiang Xue, Yilin Hu   +8 more
wiley   +1 more source

Politics and the natural resource curse: Evidence from selected African states

Cogent Social Sciences, 2022
This paper analysed political aspects of the resource curse in selected African states. The paper drew from the fact that the African region has extensive (untapped) natural resources deposits that, if utilised, can promote sustainable economic ...
C. Mlambo
doaj   +1 more source

Breaking the Trade‐Off of Mechanical Robustness and Energy Storage Capacity in Phase Change Materials Through a Molecular Design Strategy of Hard‐Segment‐Anchored/Side‐Chain‐Storage

Advanced Science, EarlyView.
To decouple mechanical robustness and energy storage capacity in phase change materials (PCMs), a series of polyurethane‐based PCMs bearing crystallizable alkyl side chains are synthesized via a hard‐segment‐anchored/side‐chain‐storage molecular design.
Huizhou Luo, Hebo Shi, Jun Zhang, Henghui Deng, Yongyin Zhu, Zehong Chen, Chaoqun Zhang   +6 more
wiley   +1 more source

Natural resource rents, energy transition and socioeconomic factors to achieve sustainable development: Novel insights from Bangladesh

Energy Conversion and Management: X
Realizing affordable and clean energy requires a global transition away from reliance on fossil fuels toward sustainable energy sources; however, the significance of natural resource rents (NRR) in this transition remains surprisingly underexplored.
Muhammad Yousaf Raza, Mohammad Maruf Hasan, Qasim Javed   +2 more
doaj   +1 more source

The KIF6‐RBP Complex Orchestrates mRNA Transport Required for Sperm Flagellar Assembly

Advanced Science, EarlyView.
Two homozygous deleterious KIF6 variants are identified in unrelated men with impaired sperm motility. Mouse models and multi‐omics analyses reveal that KIF6 cooperates with the RNA‐binding proteins FMRP and FXR1 to deliver mRNAs essential for sperm flagellar assembly, linking disrupted mRNA transport to reduced abundance of key structural and ...
Chunbo Xie, Sibing Yi, Xinle Lin, Shen Zhang, Weili Wang, Shimin Yuan, Lanlan Meng, Yong Li, Chen Tan, Chunjia Wei, Yanyan Yu, Yaoqiong Liang, Huan Zhang, Liang Hu, Guangxiu Lu, Wenbin He, Qianjun Zhang, Juan Du, Ge Lin, Chaofeng Tu, Yue‐Qiu Tan   +20 more
wiley   +1 more source