Results 31 to 40 of about 9,458,120 (261)

Drivers of wildfire suppression costs : a literature review

The purpose of this report is to provide the Washington State Department of Natural Resources (WADNR) with a literature review of key drivers of wildfire suppression costs to support improved state-level analyses in the ...
Gordon, Sean, Hunt, Ayn S., Oregon State University. Institute for Natural Resources   +2 more
core   +5 more sources

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

Molecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura, Tadahiro Kuribayashi, Johannes Brägelmann, Sachi Okawa, Masataka Taoka, Shunta Mori, Tomoka Nishimura, Takaaki Tanaka, Go Makimoto, Kiichiro Ninomiya, Kammei Rai, Eiki Ichihara, Ryohei Katayama, Katsuyuki Hotta, Masahiro Tabata, Yosuke Togashi, Yoshinobu Maeda, Martin L. Sos, Katsuyuki Kiura, Kadoaki Ohashi   +19 more
wiley   +1 more source

Biodiversity in intensive and extensive grasslands in Finland: the impacts of spatial and temporal changes of agricultural land use

Agricultural and Food Science, 2020
Biodiversity degradation is a national and global problem which is interconnected with land use and climate change. All these are major unsolved questions and their interactions are only partly understood.
Juha Tiainen, Terho Hyvönen, Marleena Hagner, Erja Huusela-Veistola, Pauliina Louhi, Antti Miettinen, Tiina Nieminen, Ansa Palojärvi, Tuomas Seimola, Pauliina Taimisto, Perttu Virkajärvi   +10 more
doaj   +1 more source

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

Molecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park, Kyongman An, Gyeonghwa Kim, Soo‐Nyun Choi, Hong‐Ki Lee, Keun Hur, Kyu‐Shik Jeong   +6 more
wiley   +1 more source

Swift recovery of Sphagnum carpet and carbon sequestration after shallow Sphagnum biomass harvesting [PDF]

Mires and Peat, 2017
White horticultural peat is a microbiologically active growing medium which binds significant quantities of nutrients and water due to its favourable cation exchange capacity and porosity.
N. Silvan, K. Jokinen, J. Näkkilä, R. Tahvonen   +3 more
doaj   +1 more source

Fifth survey on weed flora in spring cereals in Finland

Agricultural and Food Science, 2023
Regular weed surveys provide information on changes in weed communities. The composition of weed flora in spring cereal fields was investigated in southern and central Finland during 2020–2022.
Jukka Salonen, Heikki Jalli, Anne Muotila, Mari Niemi, Hannu Ojanen, Pentti Ruuttunen, Terho Hyvönen   +6 more
doaj   +1 more source

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

FEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei, Fredrik Orädd, Konstantinos Magkakis, Magnus Andersson   +3 more
wiley   +1 more source

Versatile vector tools for efficient protein screening across multiple expression systems

FEBS Open Bio, EarlyView.
A unified vector toolkit enables rapid protein expression screening across E. coli, insect, and mammalian cells. A single primer pair amplifies the target gene, which is inserted into any vector via a standardized interface. This streamlined workflow eliminates repeated cloning steps, accelerating the identification of optimal expression conditions for
Zhimin Zhu, Yaqing Liu, Lei Qin, Feng Yu, Qisheng Wang, Yahui Liu   +5 more
wiley   +1 more source

A computationally efficient method for approximating reliabilities in large-scale single-step genomic prediction

Genetics Selection Evolution, 2023
Background In this study, computationally efficient methods to approximate the reliabilities of genomic estimated breeding values (GEBV) in a single-step genomic prediction model including a residual polygenic (RPG) effect are described.
Hongding Gao, Andrei A. Kudinov, Matti Taskinen, Timo J. Pitkänen, Martin H. Lidauer, Esa A. Mäntysaari, Ismo Strandén   +6 more
doaj   +1 more source

Cyclic azapeptide CD36 ligand attenuates cardiac injury and reduces long‐chain fatty acid accumulation after myocardial ischemia–reperfusion in mice

FEBS Open Bio, EarlyView.
In a murine model of myocardial ischemia and reperfusion (MI/R), the CD36 azapeptide ligand MPE‐298 reduces cardiac injury and transiently lowers left ventricular long‐chain fatty acids (LCFAs) accumulation 3 h after reperfusion, accompanied by a decrease of oxidative stress and inflammation‐associated genes' expression in the heart and adipose tissue.
Jade Gauvin, Naghme Radmannia, David N. Huynh, Liliane Ménard, Caroline Daneault, Maïté Veilleux, Ahsanullah Ahsanullah, André C. Carpentier, William D. Lubell, Matthieu Ruiz, Huy Ong, Sylvie Marleau, Simon‐Pierre Gravel   +12 more
wiley   +1 more source