Results 101 to 110 of about 5,749,580 (311)
Hume, the Philosophy of Science and the Scientific Tradition [PDF]
, 2018 Although the main focus of Hume’s career was in the humanities, his work also has an observable role in the historical development of natural sciences after his time.
Slavov, Matias
core +2 more sources
TREX1, a predator for treating MSI‐H tumors?
Molecular Oncology, EarlyView.Immunotherapy benefits many patients; yet, some with MSI‐H tumors remain unresponsive despite their high immunogenicity. Xu et al. reveal that TREX1 enables immune evasion by degrading cytosolic DNA and suppressing cGAS–STING–IFN‐I signaling. TREX1 loss restores DNA sensing, increases CD8+ T and NK cell infiltration, and boosts antitumor immunity ...
Elena Benidovskaya +2 more
wiley +1 more source
Towards Economics as a Natural Science [PDF]
A hypothesis has been suggested for economics to become a natural science. The object of the science would be the system of reproduction of the life of people. The source of data would be the vague perceptions of experts.
Yuri Maksimenko
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Molecular Oncology, EarlyView.Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee +8 more
wiley +1 more source
Robust study design is as important on the social as it is on the ecological side of applied ecological research [PDF]
, 2014 1. The effective management of natural systems often requires resource users to change their behaviour. This has led to many applied ecologists using research tools developed by social scientists.
Jones, Julia P.G. +3 more
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Protein O‐glycosylation in the Bacteroidota phylum
FEBS Open Bio, EarlyView.Species of the Bacteroidota phylum exhibit a unique O‐glycosylation system. It modifies noncytoplasmic proteins on a specific amino acid motif with a shared glycan core but a species‐specific outer glycan. A locus of multiple glycosyltransferases responsible for the synthesis of the outer glycan has been identified.
Lonneke Hoffmanns +2 more
wiley +1 more source
Diffusion‐based size determination of solute particles: a method adapted for postsynaptic proteins
FEBS Open Bio, EarlyView.We present a diffusion‐based approach for measuring the size of macromolecules and their complexes, and demonstrate its use on postsynaptic proteins. The method requires fluorescein‐labelled protein samples, a microfluidic device that maintains laminar flow for said samples, a microscope recording the emitted fluorescent signals, and an analytic ...
András László Szabó +7 more
wiley +1 more source
RELIGION AND SCIENCE IN DIALOGUE: AN ASIAN CHRISTIAN VIEW
Zygon, 2016 We may understand natural science as part of the attempt by human beings to understand themselves and their place in the world in which they find themselves. In this sense, as Karl Rahner has suggested, natural science flows naturally into anthropology.
doaj +2 more sources
Analysis of projects funded by the National Natural Science Foundation of China during the years of 2014–2018 [PDF]
, 2019 Yihong Liu +5 more
openalex +1 more source
Effects of behavioral response and vaccination policy on epidemic spreading - an approach based on evolutionary-game dynamics [PDF]
, 2014 date of Acceptance: 23/06/2014 This work was supported by the National Natural Science Foundation of China (Grant Nos. 11331009, 11135001, 11105025). Y.-C.L. was supported by AFOSR under Grant No.
Lai, Ying-Cheng +3 more
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