Molecular Oncology, EarlyView.AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou +5 more
wiley +1 more source
ACADEMY OF NATURAL SCIENCES OF PHILADELPHIA, FEBRUARY 25 [PDF]
, 1896 Edw. J. Nolan
openalex +3 more sources
Expanding collaborative autoethnography into the world of natural science for transdisciplinary teams. [PDF]
One Earth, 2022 Haeffner M +5 more
europepmc +1 more source
The Organization and Cell-lineage of the Ascidian Egg . By Professor E. G. Conklin, Journal of the Academy of Natural Sciences of Philadelphia, Second Series, Volume XIII., Part I., 1905. [PDF]
, 1906 C. M. Child
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Decrypting cancer's spatial code: from single cells to tissue niches
Molecular Oncology, EarlyView.Spatial transcriptomics maps gene activity across tissues, offering powerful insights into how cancer cells are organised, switch states and interact with their surroundings. This review outlines emerging computational, artificial intelligence (AI) and geospatial approaches to define cell states, uncover tumour niches and integrate spatial data with ...
Cenk Celik +4 more
wiley +1 more source
Academy of Natural Sciences of Philadelphia, April 21 [PDF]
, 1896 Edw. J. Nolan
openalex +3 more sources
A Social, Not a Natural Science: Engaging With Broader Fields in Health Policy Analysis Comment on "Modelling the Health Policy Process: One Size Fits All or Horses for Courses?" [PDF]
Int J Health Policy Manag, 2023 Parkhurst J.
europepmc +1 more source
The Development of the Exact Natural Sciences in the Nineteenth Century [PDF]
, 1901 Harry C. Jones
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Molecular Oncology, EarlyView.This study indicates that Merkel cell carcinoma (MCC) does not originate from Merkel cells, and identifies gene, protein & cellular expression of immune‐linked and neuroendocrine markers in primary and metastatic Merkel cell carcinoma (MCC) tumor samples, linked to Merkel cell polyomavirus (MCPyV) status, with enrichment of B‐cell and other immune cell
Richie Jeremian +10 more
wiley +1 more source