Results 41 to 50 of about 2,099,317 (301)
Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley +1 more source
This study aims to develop AstroMotion media that are valid, practical, and effective in improving students' critical thinking skills in Natural Science learning.
Anggi Putri Utami +1 more
doaj +1 more source
Multidrug transporters BpeB and BpeF from the Gram‐negative pathogen Burkholderia pseudomallei have a hydrophilic patch in their substrate‐binding pocket. Drug susceptibility tests and growth curve analyses using an Escherichia coli recombinant expression system revealed that the hydrophilic patches of BpeB and BpeF are involved in the substrate ...
Ui Okada, Satoshi Murakami
wiley +1 more source
Function‐driven design of a surrogate interleukin‐2 receptor ligand
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang +9 more
wiley +1 more source
Introduction to University Calculus for “Bunkei’’ Students in Waseda
In these days, mathematics is one of the most important tools for any person. However, in Japan, many students hate and avoid mathematics in their high school age. In Waseda University, one of the biggest and oldest private universities in Japan, special
Takuya Sobukawa +2 more
doaj +1 more source
PEDAGOGICAL POTENTIAL OF THE EDUCATIONAL PROCESS IN STIMULATING A POSITIVE AND ACTIVE ATTITUDE TO THE ENRICHMENT OF BIOLOGY COMPETENCE OF FUTURE BACHELORS OF NATURAL SCIENCES [PDF]
Nadiia Gramatyk
openalex +1 more source
Mechanisms of parasite‐mediated disruption of brain vessels
Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira +3 more
wiley +1 more source
Knowledge Mobilization in the Beaver Hills Biosphere, Alberta, Canada
This study explores how knowledge was and is mobilized to advance the objectives of the Beaver Hills Biosphere Reserve, located in Alberta, Canada. Established in 2016, a 12-year collaborative effort worked to establish the biosphere reserve and achieve ...
Clara-Jane Blye +3 more
doaj +1 more source
Time after time – circadian clocks through the lens of oscillator theory
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo +2 more
wiley +1 more source

