Results 111 to 120 of about 2,187,661 (338)

The fidelity of dynamic signaling by noisy biomolecular networks [PDF]

, 2013
This is the final version of the article. Available from Public Library of Science via the DOI in this record.Cells live in changing, dynamic environments.
A Eldar, A Hilfinger, AH Brivanlou, B Hu, CG Bowsher, CG Bowsher, CG Bowsher, Clive G. Bowsher, CP Barnes, E Libby, F Tostevin, F Tostevin, G Balázsi, Jason M. Haugh, JC Anderson, L Steidler, M Thattai, M Voliotis, Margaritis Voliotis, N Rosenfeld, P Hersen, P Purnick, PB Detwiler, Peter S. Swain, PS Swain, R Cheong, S Tănase-Nicola, T Erdmann, T Shaw, TJ Kobayashi, TJ Perkins, V Shahrezaei, V Shahrezaei, W Bialek, W de Ronde, YT Maeda   +35 more
core   +5 more sources

Natural supramolecular protein assemblies.

Chemical Society Reviews, 2016
Supramolecular protein assemblies are an emerging area within the chemical sciences, which combine the topological structures of the field of supramolecular chemistry and the state-of-the-art chemical biology approaches to unravel the formation and ...
B. Pieters, Mark B van Eldijk, R. Nolte, J. Mecinović   +3 more
semanticscholar   +1 more source

Strength through diversity: how cancers thrive when clones cooperate

Molecular Oncology, EarlyView.
Intratumor heterogeneity can offer direct benefits to the tumor through cooperation between different clones. In this review, Kuiken et al. discuss existing evidence for clonal cooperativity to identify overarching principles, and highlight how novel technological developments could address remaining open questions.
Marije C. Kuiken, Maartje Witsen, Emile E. Voest, Krijn K. Dijkstra   +3 more
wiley   +1 more source

Astrocyte-to-neuron interaction via NF-κB/C3/C3aR mediates chronic post-thoracotomy pain by modulating neuronal GluR1 in spinal dorsal horn

iScience
Summary: Chronic post-thoracotomy pain (CPTP) is a debilitating postoperative complication associated with persistent hypersensitivity and neuroinflammatory changes.
Wanying Mou, Ning Yu, Fengrun Sun, Huan Cui, Hanyu Zhang, Yan Cao, Sixuan Jin, Chao Ma, Afang Zhu, Lulu Ma, Yuguang Huang   +10 more
doaj   +1 more source

Epistemological Analysis of Texts in Natural Sciences Textbooks: Focus on Biology

Revista Prática Docente, 2023
El presente artículo tuvo como objetivo realizar un análisis epistemológico en libros de Ciencias Naturales con enfoque en textos de Biología de la Escuela Secundaria, una investigación cualitativa del tipo revisión bibliográfica. Para llevar a cabo los análisis, se utilizaron libros de texto que conforman una colección de seis volúmenes denominada ...
Ribeiro, Fabio Neves, Coimbra, Mayco Pereira, Araújo, Vanessa Santiago, Rodrigues, Fábio Matos   +3 more
openaire   +1 more source

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

Molecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak, Karolina Pytlak, Sandra Jaworowska, Bogusz Kulawiak, Piotr Bednarczyk   +4 more
wiley   +1 more source

Profiling truncated variants of TCTN1 unveils the essential role of its integrity for ciliogenesis

iScience
Summary: Cilia protrude from the cell surface to execute signal transduction and cell motility. Tectonic (TCTN) is a transition-zone (TZ) “gatekeeper” that determines ciliary composition and function.
Huimin Yu, Lin Jiang, Chuang Xu, Ya Li, Suhui Wang, Zhao Ma, Yunyao Qian, Yiqiong Wu, Chenyu Miao, Zhouzhou Dong, Liang Wang   +10 more
doaj   +1 more source

Evolutionary Multiplayer Games

, 2014
Evolutionary game theory has become one of the most diverse and far reaching theories in biology. Applications of this theory range from cell dynamics to social evolution.
Gokhale, Chaitanya S., Traulsen, Arne
core   +1 more source

Topological Signatures in the Electronic Structure of Graphene Spirals [PDF]

, 2013
Topology is familiar mostly from mathematics, but also natural sciences have found its concepts useful. Those concepts have been used to explain several natural phenomena in biology and physics, and they are particularly relevant for the electronic ...
Avdoshenko, Stas.M., Koskinen, Pekka, Popov, Alexey A., Rocha, Claudia G., Sevincli, Haldun   +4 more
core   +3 more sources

TREX1, a predator for treating MSI‐H tumors?

Molecular Oncology, EarlyView.
Immunotherapy benefits many patients; yet, some with MSI‐H tumors remain unresponsive despite their high immunogenicity. Xu et al. reveal that TREX1 enables immune evasion by degrading cytosolic DNA and suppressing cGAS–STING–IFN‐I signaling. TREX1 loss restores DNA sensing, increases CD8+ T and NK cell infiltration, and boosts antitumor immunity ...
Elena Benidovskaya, Joséphine Deneft, Marc Van den Eynde   +2 more
wiley   +1 more source