Results 81 to 90 of about 2,187,661 (338)

Function‐driven design of a surrogate interleukin‐2 receptor ligand

FEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang, Zelin Cheng, Teng Li, Fulian Wang, Liangminghui Zhang, Xiuxiu He, Lili Liu, Wei Wang, Aibin Liang, Guang Yang   +9 more
wiley   +1 more source

Primitive to visceral endoderm maturation is essential for mouse epiblast survival beyond implantation

iScience
Summary: The implantation of the mouse blastocyst initiates a complex sequence of tissue remodeling and cell differentiation events required for morphogenesis, during which the extraembryonic primitive endoderm transitions into the visceral endoderm ...
Antonia Weberling, Dylan Siriwardena, Christopher Penfold, Neophytos Christodoulou, Thorsten E. Boroviak, Magdalena Zernicka-Goetz   +5 more
doaj   +1 more source

NATURE OF SCIENCE PROFILE OF PROSPECTIVE BIOLOGY TEACHER

Jurnal Pembelajaran Biologi: Kajian Biologi dan Pembelajarannya
This research aims to analyze the understanding of prospective biology teachers regarding the Nature of Science (NOS) as an important foundation in science education. The method used is a quantitative descriptive survey with the Views of Nature of Science (VNOS) Form B questionnaire instrument.
Eka Ariyati, null Laras, Fajar Fadilah, Anis Aulia   +3 more
openaire   +1 more source

Comparative analysis of knowledge representation and reasoning requirements across a range of life sciences textbooks. [PDF]

, 2014
BackgroundUsing knowledge representation for biomedical projects is now commonplace. In previous work, we represented the knowledge found in a college-level biology textbook in a fashion useful for answering questions.
Chaudhri, Vinay K, Elenius, Daniel, Goldenkranz, Andrew, Gong, Allison, Martone, Maryann E, Webb, William, Yorke-Smith, Neil   +6 more
core   +3 more sources

Mechanisms of parasite‐mediated disruption of brain vessels

FEBS Letters, EarlyView.
Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira, Sílvia Arroz‐Madeira, Cláudio A. Franco, Sara Silva Pereira   +3 more
wiley   +1 more source

Time after time – circadian clocks through the lens of oscillator theory

FEBS Letters, EarlyView.
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo, Carolin Ector, Hanspeter Herzel   +2 more
wiley   +1 more source

Role of Virtual Reality in Geography and Science Fieldwork Education [PDF]

, 2018
Fieldwork has a long tradition in geography, and in certain sciences, notably geology, biology and environmental sciences. Fieldwork involves leaving the classroom and engaging in learning and teaching through first-hand experience of phenomena in ...
Minocha, Shailey, Tilling, Steve, Tudor, Ana-Despina   +2 more
core  

A multi-perspective analysis of retractions in life sciences

Scientometrics, 2020
The aim of this study is to explore trends in retracted publications in life sciences and biomedical sciences over axes like time, countries, journals and impact factors, and topics.
B. Bhatt
semanticscholar   +1 more source

Cell wall target fragment discovery using a low‐cost, minimal fragment library

FEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan, Mathew Stanley, Olawale Raimi, Andrew T. Ferenbach, Helge C Dorfmueller, Daan M. F. van Aalten   +5 more
wiley   +1 more source

Exploring the Nature of Science Representations in Biology Textbooks

International Journal on Studies in Education
The aim of this study is to explore how nature of science is addressed in biology textbooks according to grade level and the chapters. The textbooks examined within the scope of the study are Biology 9 and Biology 10 textbooks. The analysis of the textbooks was based on the Reconceptualized Family Resemblance Approach.
Seyda Gul, Suat Celik
openaire   +1 more source