Results 131 to 140 of about 5,371,893 (343)

Unraveling LINE‐1 retrotransposition in head and neck squamous cell carcinoma

Molecular Oncology, EarlyView.
The novel RetroTest method allows the detection of L1 activation in clinical samples with low DNA input, providing global L1 activity and the identification of the L1 source element. We applied RetroTest to a real‐world cohort of HNSCC patients where we reported an early L1 activation, with more than 60% of T1 patients showing L1 activity.
Jenifer Brea‐Iglesias, Ana Oitabén, Sonia Zumalave, Bernardo Rodriguez‐Martin, María Gallardo‐Gómez, Martín Santamarina, Ana Pequeño‐Valtierra, Laura Juaneda‐Magdalena, Ramón García‐Escudero, José Luis López‐Cedrún, Máximo Fraga, José M. C. Tubio, Mónica Martínez‐Fernández   +12 more
wiley   +1 more source

Cutting-edge microneedle innovations: Transforming the landscape of cardiovascular and metabolic disease management

iScience
Summary: Cardiovascular diseases (CVDs) and metabolic disorders (MDs) have surfaced as formidable challenges to global health, significantly imperiling human well-being. Recently, microneedles (MNs) have garnered substantial interest within the realms of
Xiaoning Zhang, Ming Li, Qiang Gao, Xiaoya Kang, Jingyao Sun, Yao Huang, Hong Xu, Jing Xu, Songren Shu, Jian Zhuang, Yuan Huang   +10 more
doaj  

Emerging advances in biosecurity to underpin human, animal, plant, and ecosystem health

iScience, 2023
Summary: One Biosecurity is an interdisciplinary approach to policy and research that builds on the interconnections between human, animal, plant, and ecosystem health to effectively prevent and mitigate the impacts of invasive alien species.
Philip E. Hulme, Jacqueline R. Beggs, Rachelle N. Binny, Jonathan P. Bray, Naomi Cogger, Manpreet K. Dhami, Susanna C. Finlay-Smits, Nigel P. French, Andrea Grant, Chad L. Hewitt, Eirian E. Jones, Phil J. Lester, Peter J. Lockhart   +12 more
doaj  

What is Science? [PDF]

arXiv, 2017
This paper proposes a new definition of science based on the distinction between the activity of scientists and the product of that activity: the former is denoted (lower-case) science and the latter (upper-case) Science. These definitions are intended to clarify the nature of scientific knowledge, its authority as well as its limitations, and how ...
arxiv  

Natural Science for Women [PDF]

, 1880
ALFRED W. BENNETT
openalex   +1 more source

A deeper look into natural sciences with physics-based and data-driven measures. [PDF]

iScience, 2021
Rodrigues DR, Everschor-Sitte K, Gerber S, Horenko I.   +3 more
europepmc   +1 more source

Natural Science [PDF]

Science, 1973
openaire   +4 more sources

Tumor clusters with divergent inflammation and human retroelement expression determine the clinical outcome of patients with serous ovarian cancer

Molecular Oncology, EarlyView.
Analysis of treatment‐naïve high‐grade serous ovarian carcinoma (HGSOC) and control tissues for ERVs, LINE‐1 (L1), inflammation, and immune checkpoints identified five clusters with diverse patient recurrence‐free survivals. An inflammation score was calculated and correlated with retroelement expression, where one novel cluster (Triple‐I) with high ...
Laura Glossner, Markus Eckstein, Christoph Mark, Matthias W. Beckmann, Arndt Hartmann, Pamela L. Strissel, Reiner Strick   +6 more
wiley   +1 more source

Dynamics of the oral microbiome during orthodontic treatment and antimicrobial advances for orthodontic appliances

iScience
Summary: The oral microbiome plays an important role in human health, and an imbalance of the oral microbiome could lead to oral and systemic diseases. Orthodontic treatment is an effective method to correct malocclusion.
Qin Niu, Si Chen, Rushui Bai, Yuntao Lu, Liying Peng, Bing Han, Tingting Yu   +6 more
doaj  

Natural Science in Hygiene, or the Life-History of the Non-Bacterial Parasites affecting Man [PDF]

, 1906
R. T. HEWLETT
openalex   +1 more source