Results 181 to 190 of about 12,832,013 (404)

Call to arms for shaking up social sciences relies on false premise that science alone can solve all social problems. [PDF]

, 2014
A new form of ‘interdisciplinarity’ may be emerging but has so far failed to devote equal demands on the natural sciences, as well as on the social sciences. Will Davies responds to the calls for a social science shake-up by questioning the status of the
Davies, Will
core  

DDX3X induces mesenchymal transition of endothelial cells by disrupting BMPR2 signaling

FEBS Open Bio, EarlyView.
Elevated DDX3X expression led to downregulation of BMPR2, a key regulator of endothelial homeostasis and function. Our co‐immunoprecipitation assays further demonstrated a molecular interaction between DDX3X and BMPR2. Notably, DDX3X promoted lysosomal degradation of BMPR2, thereby impairing its downstream signaling and facilitating endothelial‐to ...
Yu Zhang, Jing Wang, De‐Hui Qian, Yang‐Fan Lv, Tian‐Le Cheng, Da‐Peng Wang, Jing Zhang, Ye Fan   +7 more
wiley   +1 more source

A graphene-based photo-electro-thermal metamaterial for soft fixtures with superior grasping performance

iScience
Summary: Soft actuators are valued for their adaptability and diverse applications but often face challenges like slow response, high activation energy, and high energy consumption.
Bowen Yang, Xuanchen Dong, Wenhao Lv, Wenzhuo Liu, Mengying Lu, Zhe Liu, Tonghui Lu, Xianglin Li, Song Lv   +8 more
doaj   +1 more source

Equal Representation Does Not Mean Equal Opportunity: Women Academics Perceive a Thicker Glass Ceiling in Social and Behavioral Fields Than in the Natural Sciences and Economics. [PDF]

Front Psychol, 2022
van Veelen R, Derks B.
europepmc   +1 more source

Antibiofilm activity of a chionodracine‐derived peptide by NMR‐based metabolomics of cell‐free supernatant of Acinetobacter baumannii clinical strains

FEBS Open Bio, EarlyView.
KHS‐Cnd peptide is able to impair biofilm formation and disaggregate mature biofilms in Acinetobacter baumannii clinical isolates. Differences in extracellular metabolites reflect changes in biofilm metabolism due to KHS‐Cnd treatment. Among the differentially represented extracellular metabolites upon KHS‐Cnd treatment, the significantly altered ...
Fernando Porcelli, Enrico Landi, Francesco Maiurano, Irene Paris, Rosanna Papa, Marco Artini, Laura Selan, Stefano Borocci, Francesco Buonocore, Esther Imperlini   +9 more
wiley   +1 more source

The role of deep learning in myocardial perfusion imaging for diagnosis and prognosis: A systematic review

iScience
Summary: The development of state-of-the-art algorithms for computer visualization has led to a growing interest in applying deep learning (DL) techniques to the field of medical imaging.
Xueping Hu, Han Zhang, Federico Caobelli, Yan Huang, Yuchen Li, Jiajia Zhang, Kuangyu Shi, Fei Yu   +7 more
doaj   +1 more source

Science and Ethics (From the Perspective of Natural Sciences)

, 2015
M. A. Shishkin
openalex   +2 more sources

Down‐regulation of Shh in the hair follicles of mice during chemotherapy‐induced hair loss is mediated by the JAK/STAT1 signaling pathway

FEBS Open Bio, EarlyView.
We found that during chemotherapy‐induced alopecia (CIA), Sonic hedgehog (Shh) expression significantly decreased in hair follicle Shh+ cells, whereas the Janus‐activated kinase/signal transducer and activator of transcription 1 (JAK/STAT1) signaling pathway was markedly activated.
Ruifang Fan, Jingling Huang, Xiang Lin, Tingjiao Lan, Yuli Tang, Ling Sun, Guixuan Zhou   +6 more
wiley   +1 more source

Information and communication technology pedagogical practices of South African Grade 8 Mathematics and Natural Science teachers

, 2016
James Varughese, A. Seugnet Blignaut, J. Christo   +2 more
openalex   +1 more source

Engineering tandem VHHs to target different epitopes to enhance antibody‐dependent cell‐mediated cytotoxicity

FEBS Open Bio, EarlyView.
Tandem VHH targeting distinct EGFR epitopes were engineered into a monovalent bispecific antibody (7D12‐EGA1‐Fc) with more potent ADCC without increasing affinity to EGFR. Structural modeling of 7D12‐EGA1‐Fc showed cross‐linking of separate EGFR domains to enhance CD16a engagement on NK cells.
Yuqiang Xu, Hao Jiang, Limin Chen, Fulai Zhou, Ying Jin, Mark L. Chiu   +5 more
wiley   +1 more source