Results 191 to 200 of about 12,832,013 (404)
We investigated the toxicity of 12 active compounds commonly found in herbal weight loss supplements (WLS) using human liver and colon cell models. Epigallocatechin‐3‐gallate was the only compound showing significant toxicity. Metabolic profiling revealed protein degradation, disrupted energy and lipid metabolism suggesting that the inclusion of EGCG ...
Emily C. Davies +3 more
wiley +1 more source
Spirocyclic Nitroxides as Versatile Tools in Modern Natural Sciences: From Synthesis to Applications. Part I. Old and New Synthetic Approaches to Spirocyclic Nitroxyl Radicals. [PDF]
Zaytseva EV, Mazhukin DG, Mazhukin DG.
europepmc +1 more source
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point +7 more
wiley +1 more source
The Problem of Climate Change: The Field of Convergence and Interaction between Natural Sciences and the Sociohumanities. [PDF]
Danilov-Danil'yan VI +2 more
europepmc +1 more source
SHEETS-PYENSON, Susan, Cathedrals of Science: The Development of Colonial Natural History Museums During the Late Nineteenth Century. Montréal, McGill-Queen’s University Press, 1988. 144 p. 24,95 $ [PDF]
Alain Canuel
openalex +1 more source
Aged human bmMSCs are seeded in the scaffold. Osteoblastic induction can slightly increase cell's bone‐forming activity to produce bone‐like tissues, shown as the sporadic xylenol orange‐stained spots (the lower left image). Notably, pioglitazone plus EGCG co‐treatment dramatically increases cell's bone‐forming activity and bone‐like tissue production (
Ching‐Yun Chen +6 more
wiley +1 more source
dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon +6 more
wiley +1 more source
Researcher-Led Development of E-Research in the Social Sciences: The Case of an E-Social Science Pilot Demonstrator Project [PDF]
The introduction and use of information and communication technologies (ICT) in the process of research is extending beyond research management into research practice itself. This extension of the use of ICT in research is being termed as e-research. The
Bridgette Wessels, Max Craglia
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