Results 191 to 200 of about 12,580,279 (393)

Preparation and characterization of renal cell peptides from fetal rats for their antitumor activity

open access: yesFEBS Open Bio, EarlyView.
This study aimed to prepare renal cells (RCs) from fetal rats which were digested by enzymes. Candidate peptides RCPs were characterized by capillary HPLC and MS and their bioactivity was predicted using peptideranker. The predicted top 10 bioactive peptides were synthesized.
Zhe Zhang   +6 more
wiley   +1 more source

Call to arms for shaking up social sciences relies on false premise that science alone can solve all social problems. [PDF]

open access: yes, 2014
A new form of ‘interdisciplinarity’ may be emerging but has so far failed to devote equal demands on the natural sciences, as well as on the social sciences. Will Davies responds to the calls for a social science shake-up by questioning the status of the
Davies, Will
core  

A semi-supervised method using cycle consistency and multi-perspective dilated for SAR-to-optical translation

open access: yesiScience
Summary: Synthetic aperture radar (SAR) is a powerful imaging sensor capable of operating in any weather and at any time, despite its image interpretation poses challenges.
Jinyu Wang   +3 more
doaj   +1 more source

Ro 31‐8220 suppresses bladder cancer progression via enhancing autophagy in vitro and in vivo

open access: yesFEBS Open Bio, EarlyView.
The pan‐protein kinase C inhibitor Ro‐31‐8220 demonstrates potent anti‐bladder cancer effects both in vitro and in vivo by suppressing migration/invasion, inducing apoptosis and crucially activating autophagy, where blocking autophagy with chloroquine reduces its cell‐killing efficacy, suggesting its promise as a novel therapeutic candidate requiring ...
Shengjun Fu   +12 more
wiley   +1 more source

Non-foundational criticality? On the need for a process ontology of the psychosocial [PDF]

open access: yes, 2007
The articulation of critical dialects of psychology has typically involved a questioning of the foundational assumptions of the so-called mainstream. This has included critiques in the name of more adequate scientific foundations, but more recently these
Stenner, P.
core   +1 more source

Differential substrate degradation by super-degron: EGFP in wild-type mouse cells, PD-1 requires CRBN humanization

open access: yesiScience
Summary: Protein knockdown using a zinc finger degron tag and thalidomide analogs was previously considered ineffective in mouse cells. However, using EGFP as an indicator, we found that a super-degron tag (SD) enables degradation in mouse cells when ...
Chie Naruse   +10 more
doaj   +1 more source

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