Results 121 to 130 of about 1,660,917 (306)

dUTPase is essential in zebrafish development and possesses several single‐nucleotide variants with pronounced structural and functional consequences

open access: yesFEBS Open Bio, EarlyView.
dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon   +6 more
wiley   +1 more source

Growth in well-stocked natural oak stands in Missouri [PDF]

open access: yes, 1959
This bulletin reports on School of Forestry Research Project 124, Timber Economics--P. [2].Digitized 2007 AES.Includes bibliographical references (pages 19-20)
Nash, Andrew J. (Andrew Joseph), 1918-
core  

Enzymatic degradation of biopolymers in amorphous and molten states: mechanisms and applications

open access: yesFEBS Open Bio, EarlyView.
This review explains how polymer morphology and thermal state shape enzymatic degradation pathways, comparing amorphous and molten biopolymer structures. By integrating structure–reactivity principles with insights from thermodynamics and enzyme engineering, it highlights mechanisms that enable efficient polymer breakdown.
Anđela Pustak, Aleksandra Maršavelski
wiley   +1 more source

To Understand Where Humankind Stands in Nature

open access: yesAnthropological Science (Japanese Series), 2008
現在新しい学習指導要領の改訂作業が進んでいる。このようなときに,現行の学習指導要領の問題点を総括することは,次期学習指導要領を考えていく上で重要である。現行の指導要領においては,理科に当てる時数が少ないために「DNA」などを学ぶことなく終わったり,生物Iを履修してもその中に含まれない「進化」や「代謝」「生態」などは,生物IIを履修しないと学べない。かつて行われていた「生物IA」(ヒトの生物学)という科目は,ヒトを対象に総合的に見る幅広いカリキュラムであった。そのような科目が定着しなかったのは,そのアプローチが中途半端であったこと,入試において重要視されなかったことなどがあげられる。しかし,ヒトである自分自身を知ることは生徒の興味を引かせ,そこを入り口に生物の多様性 ...
openaire   +2 more sources

Perbandingan Unit Contoh Lingkaran Dan Tree Sampling Dalam Menduga Potensi Tegakan Hutan Tanaman Rakyat Pinus (Studi Kasus Desa Pondok Buluh, Kecamatan Dolok Panribuan, Kabupaten Simalungun) [PDF]

open access: yes, 2012
Information on the potential of forest stands is necessary to know the state and the amount of natural resources contained therein. Potential stands a forest area estimates can be obtained by various methods.
Afifuddin, Y. (Yunus)   +2 more
core  

Anticancer sensitivities and biological characteristics of HCT116 cells resistant to the selective poly(ADP‐ribose) glycohydrolase inhibitor

open access: yesFEBS Open Bio, EarlyView.
We analyzed alterations of PAR metabolism‐related proteins in PARG inhibitor‐resistant HCT116RPDD cells. Although PARG levels remained unchanged, HCT116RPDD cells exhibited reduced PARP1 and ARH3 expression and elevated PAR levels. Interestingly, HCT116RPDD cells exhibited slightly elevated intracellular NAD+/NADH and ATP levels. Our findings suggest a
Kaede Tsuda, Yoko Ogino, Akira Sato
wiley   +1 more source

Standing With Nature [PDF]

open access: yesEcological Restoration, 1992
openaire   +1 more source

Bilateralism: Negations, Implications and some Observations and Problems about Hypotheses [PDF]

open access: yes, 2017
This short paper has two loosely connected parts. In the first part, I discuss the difference between classical and intuitionist logic in relation to different the role of hypotheses play in each logic.
Kürbis, Nils
core  

Understanding bio‐based polymers: A study of origins, properties, biodegradation and their impact on health and the environment

open access: yesFEBS Open Bio, EarlyView.
This review provides an overview of bio‐based polymer sources, their unique functional properties and their environmental impact, and addresses their role as sustainable alternatives. It discusses end‐of‐life options, including composting and anaerobic digestion for renewable energy.
Sabina Kolbl Repinc   +8 more
wiley   +1 more source

HIV‐1 establishes immediate latency in T cells expressing the viral Nef protein

open access: yesFEBS Open Bio, EarlyView.
Nef is a viral protein often omitted from HIV‐1 reporter viruses. Consequently, its role in viral latency is unclear. We developed three novel dual reporter HIV‐1 derivatives that express Nef and allow for detection of latent and productive infection. Using these reporters, we show that Nef does not affect the establishment of immediate viral latency ...
Cindy Lam, Ivan Sadowski
wiley   +1 more source

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