Results 281 to 290 of about 4,559,471 (378)

Experimental study on burning rate and flame geometry in construction tunnel fires under high geothermal conditions

open access: yesDeep Underground Science and Engineering, EarlyView.
Abstract As tunnel construction advances in lengths and depths, the construction of tunnels in high geothermal environments has become increasingly common, raising significant fire risks. In this study, a 1:20 scale model tunnel test platform was constructed to investigate the effects of a high geothermal environment on fire behavior in tunnels during ...
Xiaoxian Fei   +6 more
wiley   +1 more source

Multiple injection techniques to stimulate complex fracture networks in coal reservoirs: A case study on gas disaster reduction of subsurface coal mine in southwest China

open access: yesDeep Underground Science and Engineering, EarlyView.
An experimental device for physical simulation of hydraulic fracturing, comprising: a load‐bearing mechanism with multiple interconnected plates that collectively form an sample chamber; a load‐generating mechanisms, with multiple load‐generating mechanisms arranged within the experimental chamber.
Delei Shang   +5 more
wiley   +1 more source

DSOK‐0011 Potentially Regulates Circadian Misalignment and Affects Gut Microbiota Composition in Activity‐Based Anorexia Model

open access: yesInternational Journal of Eating Disorders, EarlyView.
ABSTRACT Objective Anorexia nervosa (AN) is a metabolic‐psychiatric disorder characterized by severe weight loss, hypercortisolemia, and hypothalamic–pituitary–adrenal (HPA) axis activation. In this study, we investigated the effect of inhibiting cortisol regeneration via the enzyme 11β‐hydroxysteroid dehydrogenase type 1 (11β‐HSD1) on the ...
Hiroki Kawai   +15 more
wiley   +1 more source

Association of COPD with adverse outcomes in heart failure patients with preserved ejection fraction

open access: yesESC Heart Failure, Volume 12, Issue 2, Page 799-808, April 2025.
Abstract We performed a systematic review and meta‐analysis to detect the impact of chronic obstructive pulmonary disease (COPD) on the prognosis of heart failure patients with preserved ejection fraction (HFpEF). We systematically screened eligible literature from three electronic databases, PubMed, EMBASE and Cochrane Library, up to April 2023.
Shuo Xu   +3 more
wiley   +1 more source

Considerations for drug trials in hypertrophic cardiomyopathy

open access: yesESC Heart Failure, Volume 12, Issue 2, Page 1095-1112, April 2025.
Abstract Hypertrophic cardiomyopathy (HCM) is a heterogeneous condition with potentially serious manifestations. Management has traditionally comprised therapies to palliate symptoms and implantable cardioverter‐defibrillators to prevent sudden cardiac death. The need for disease‐modifying therapies has been recognized for decades.
John P. Farrant   +17 more
wiley   +1 more source

Home - About - Disclaimer - Privacy