Results 61 to 70 of about 114,377 (311)

Amuc_1473 Links Gut Microbes to Skeletal Homeostasis and Counteracts Multifactorial Osteoporosis

Advanced Science, EarlyView.
Amuc_1473, a previously uncharacterized protein enriched in Akkermansia muciniphila‐derived extracellular vesicles, is identified as a gut–bone messenger that promotes osteogenesis and inhibits osteoclastogenesis by engaging transcriptional and translational regulators in bone cells.
Shan‐Shan Rao, Hai‐Jin Zeng, Zun Wang, Chun‐Gu Hong, Yi‐Juan Tan, Yan‐Xin Duan, Jing‐Yao Luo, Ming‐Jie Luo, Yi‐Wei Liu, Xin Wang, Yi Luo, Teng‐Fei Wan, Yong Zhou, Zheng‐Guang Wang, Guo‐Wen Hu, Hao Yin, Xin‐Yue Hu, Zhen‐Xing Wang, Ze‐Hui He, Si‐Yi Cheng, Wei Du, Zhe Guan, Hai‐Li Lang, Hong‐Ji Liu, Jia Cao, Peng Chen, Jiang‐Hua Liu, Hui Xie, Chun‐Yuan Chen   +28 more
wiley   +1 more source

Review of natural ventilation models [PDF]

, 2016
Natural ventilation (NV) is an important and efficient passive technique toreduce building cooling energy need and improve indoor air quality. NVdesign requires profound knowledge and accurate prediction of air flowand heat transfer in and around ...
Johnson, M.-H., El Mankibi, M., Zhai, Z.,, Stathopoulos, Nikolaos, Johnson, M.-H.,, Stathopoulos, Nikolaos,, Zhai, Z., El Mankibi, M.,   +7 more
core   +1 more source

TME/NIR Dual‐Responsive Zinc‐Based Targeted Nanoagonist for Multimodal Amplification of STING‐Mediated Cancer Immunotherapy

Advanced Science, EarlyView.
A multifunctional nanoagonist (cDZ@IP) enables nano‐metabolite–driven multimodal activation of the STING pathway and enhanced immune recognition, achieving potent antitumor immunity and suppressing tumor growth and metastasis. This strategy highlights the rational design of therapeutic metabolites and establishes a new paradigm bridging nanomedicine ...
Kepeng Hu, Jiawei Wang, Wei Zhang, Zhixuan Wu, Jing Chen, Yujing He, Xiyue Duan, Yaoting He, Xin Xin, Haoyi Xiang, Yijing Wang, Chengwei Wu, Yang Yi, Qing Meng, Yuqian Qiao, Kui Cheng, Xiaojun Long, Zhangfa Song   +17 more
wiley   +1 more source

Characterizing the chaotic nature of ocean ventilation [PDF]

Journal of Geophysical Research: Oceans, 2017
AbstractVentilation of the upper ocean plays an important role in climate variability on interannual to decadal timescales by influencing the exchange of heat and carbon dioxide between the atmosphere and ocean. The turbulent nature of ocean circulation, manifest in a vigorous mesoscale eddy field, means that pathways of ventilation, once thought to be
Graeme A. MacGilchrist, David P. Marshall, Helen L. Johnson, Camille Lique, Matthew Thomas   +4 more
openaire   +2 more sources

Celastrol‐Loaded Conductive Hydrogel Mitigates Myocardial Ischemia‐Reperfusion Injury and Restores Electrophysiological Function

Advanced Science, EarlyView.
Schematic illustration of the Pluronic F127 diacrylate/gelatin methacryloyl/poly(3,4‐ethylenedioxythiophene):poly(styrenesulfonate)/celastrol hydrogel (FGPC) for localized myocardial ischemia–reperfusion injury treatment. FGPC combines sustained celastrol delivery with PEDOT:PSS‐mediated conductive support to attenuate acute oxidative/inflammatory ...
Shixin Wang, Shaojie Chen, Chengzong Li, Hongyi Cheng, Jincheng Jiao, Xiafeng Peng, Yike Zhang, Wei Sun, Feng Zhang, Chang Cui, Minglong Chen   +10 more
wiley   +1 more source

Assessing ventilation through ambient carbon dioxide concentrations across multiple healthcare levels in Ghana.

PLOS Global Public Health
Infection prevention and control (IPC) measures safeguard primary healthcare systems, especially as the infectious disease landscape evolves due to climate and environmental change, increased global mobility, and vaccine hesitancy and inequity, which can
Cecilia Crews, Paul Angwaawie, Alhassan Abdul-Mumin, Iddrisu Baba Yabasin, Evans Attivor, John Dibato, Megan P Coffee   +6 more
doaj   +1 more source

Synchronization‐Dissipation in the Cardiorespiratory System

Advanced Science, EarlyView.
By modeling central nervous coupling and viscoelastic interactions in the cardiorespiratory system we show that synchronization produces a 10% gain in cardiac efficiency in humans. It is surmised that respiratory sinus arrhythmia improves cardiac pumping efficiency by reducing dynamic stress and power dissipation in the pulmonary vasculature.
Joshua R. Border, Alain Nogaret, Andrew Lefevre, Vishal Jain   +3 more
wiley   +1 more source

Designing for Natural Ventilation: An Early Stage Design Tool [PDF]

, 2015
Early design stage decision making proceeds very quickly, and strategic decisions regarding the feasibility of natural ventilation must be supported by speedy and reliable evaluation.
Vallejo, J., Aparicio, P., Diaz, C., Ford, B.   +3 more
core  

Macrophage‐to‐Myofibroblast Transdifferentiation Contributes to Pulmonary Fibrosis via the MERTK‐SPP1‐SRC‐TKS5 Signaling Axis

Advanced Science, EarlyView.
MERTK is upregulated in fibrotic macrophages and regulates the expression and activity of SRC and TKS5 through SPP1, mediating transdifferentiation of macrophages‐to‐myofibroblasts (MMT) and promoting pulmonary fibrosis. The figure was created with BioRender.com.
Yungeng Wei, Hua Guo, Xiangsheng Yang, Xiao Xiao Tang   +3 more
wiley   +1 more source

The integration of heat pipe technology into natural ventilation systems [PDF]

, 2013
The aim of this research was to integrate heat pipe technology into natural ventilation air streams to provide passive cooling in regions of hot arid climatic conditions without the use of mechanical assistance.
Chaudhry, Hassam Nasarullah
core