Results 191 to 200 of about 3,530,202 (329)

Molecular dynamics simulations of positively selected codons in FcγRI reveal novel biochemical binding properties

open access: yesFEBS Open Bio, EarlyView.
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young   +7 more
wiley   +1 more source

Carbon Farming: Nature-Based Solutions in Brazil

open access: diamond, 2023
Danielle Mendes Thame Denny   +3 more
openalex   +2 more sources

Nature-based solutions in planning

open access: yes, 2019
This article looks at some of the ways in which advocates of ‘nature-based solutions’ approaches have sought to inform local authority planning policies, and offer some\ud reflections on nature-based solutions in planning.
Jones, Peter, Comfort, Daphne
openaire  

Acute caffeine treatment protects the developing retina from ischemia‐induced cell death

open access: yesFEBS Open Bio, EarlyView.
Caffeine reduces cell death in the developing retina under ischemia (OGD). This effect does not involve BDNF upregulation or antioxidant pathways (NRF2/VEGF). Neuroprotection occurs mainly through adenosine A2A receptor antagonism, decreasing glutamate release and excitotoxicity, highlighting caffeine's potential as an acute neuroprotective agent in ...
Amanda Alves Nascimento   +6 more
wiley   +1 more source

Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling

open access: yesFEBS Open Bio, EarlyView.
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero   +5 more
wiley   +1 more source

Assessing the sensitivity of urban aquatic nature-based solutions to hydroclimate variability using stable water isotopes. [PDF]

open access: yesEnviron Monit Assess
Warter MM   +9 more
europepmc   +1 more source

Delta Challenges and Nature-based Solutions in Dialogue

open access: hybrid, 2022
Kim van Nieuwaal   +2 more
openalex   +2 more sources

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