Results 121 to 130 of about 17,135,626 (311)

Digital twins to accelerate target identification and drug development for immune‐mediated disorders

FEBS Open Bio, EarlyView.
Digital twins integrate patient‐derived molecular and clinical data into personalised computational models that simulate disease mechanisms. They enable rapid identification and validation of therapeutic targets, prediction of drug responses, and prioritisation of candidate interventions.
Anna Niarakis, Philippe Moingeon
wiley   +1 more source

Retracted: Research on Modern Book Packaging Design under Aesthetic Evaluation Based on Deep Learning Model

Discrete Dynamics in Nature and Society, 2023
Discrete Dynamics in Nature and Society
doaj   +1 more source

Is nature natural?

Nuclear Physics B
Contribution to "A Master's Journey through the Two Standard Models: A volume dedicated to the Memory of Steven Weinberg".
openaire   +4 more sources

Systemic dysregulation of apolipoproteins in amyotrophic lateral sclerosis serum

FEBS Open Bio, EarlyView.
Amyotrophic lateral sclerosis (ALS) is a fatal disease that damages motor neurons. This study found that people with ALS show significant changes in blood fats and the proteins that carry them. Several apolipoproteins were higher, lipid balances were altered, and normal protein–lipid relationships were disrupted.
Finula I. Isik, Russell Pickford, Hannah C. Timmins, Olivier Piguet, Glenda M. Halliday, Matthew C. Kiernan, Woojin Scott Kim   +6 more
wiley   +1 more source

Retracted: Measurement of Logistics Radiation Range and Improvement of Logistics Radiation Ability of City Clusters

Discrete Dynamics in Nature and Society
Discrete Dynamics in Nature and Society
doaj   +1 more source

Retracted: Complex Discrete System Analysis of Process Design and Tourist Souvenir Making Based on Artificial Intelligence 3D Printing

Discrete Dynamics in Nature and Society, 2023
Discrete Dynamics in Nature and Society
doaj   +1 more source

Exploring the links: environmental identity, nature connectedness, eco-anxiety and psychological well-being after the 2023 Kahramanmaraş earthquakes. [PDF]

BMC Psychol
Arpacı R, Kabakoğlu H.
europepmc   +1 more source

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

FEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane, Lea Nikolić, Lorenzo Maraio, Thomas Goiran, Nathan Karpilovsky, Stefano Sellitto, Vangelis Bouris, Jiang‐An Yin, Ronald Melki, Edward A Fon, Adriano Aguzzi, Elena De Cecco   +11 more
wiley   +1 more source

Retracted: Application of Heterogeneous Network Oriented to NoSQL Database in Optimal Postevaluation Indexes of Construction Projects

Discrete Dynamics in Nature and Society, 2023
Discrete Dynamics in Nature and Society
doaj   +1 more source

Accommodation of Biodiversity in Swedish Municipalities. A National Survey. [PDF]

Environ Manage
Christoffersen L, Englund JE, Randrup T.
europepmc   +1 more source